ArticlePloS one2016
Transcriptome Analysis of Capsicum Chlorosis Virus-Induced Hypersensitive Resistance Response in Bell Capsicum.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 31 citations in OpenAlex.
- Transcriptome Analysis of Pepper Leaves in Response to Tomato Brown Rugose Fruit Virus Infection.Plants (Basel, Switzerland) · 2025Article
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- Integrated Transcriptome and sRNAome Analysis Reveals the Molecular Mechanisms ofInternational journal of molecular sciences · 2024Article
- Involvement of MicroRNAs in the Hypersensitive Response of Capsicum Plants to the Capsicum Chlorosis Virus at Elevated Temperatures.Pathogens (Basel, Switzerland) · 2024Article
- Comprehensive transcriptomic meta-analysis unveils new responsive genes to methyl jasmonate and ethylene inHeliyon · 2024Article
- The RING-Finger Protein NbRFP1 Contributes to Regulating the Host Hypersensitive Response Induced by Oat Dwarf Virus RepA.International journal of molecular sciences · 2023Article
- Pepper Plants HarboringPlants (Basel, Switzerland) · 2022Article
- Pest categorisation of Capsicum chlorosis virus.EFSA journal. European Food Safety Authority · 2022Article
- Temporal expression of defence and susceptibility genes and tospovirus accumulation in capsicum chlorosis virus-infected capsicum.Archives of virology · 2022Article
- Effects of Elevated Temperature on the Susceptibility of Capsicum Plants to Capsicum Chlorosis Virus Infection.Pathogens (Basel, Switzerland) · 2022Article
- Transcriptome profiling of pepper leaves by RNA-Seq during an incompatible and a compatible pepper-tobamovirus interaction.Scientific reports · 2021Article
- Identification, characterization, and expression analysis of cowpea (Vigna unguiculata [L.] Walp.) miRNAs in response to cowpea severe mosaic virus (CPSMV) challenge.Plant cell reports · 2020Article
- Capsidiol-related genes are highly expressed in response to Colletotrichum scovillei during Capsicum annuum fruit development stages.Scientific reports · 2020Article
- Flagellin of Bacillus amyloliquefaciens works as a resistance inducer against groundnut bud necrosis virus in chilli (Capsicum annuum L.).Archives of virology · 2020Article
- Overview of Biotic Stresses in Pepper (International journal of molecular sciences · 2020Review
- Glutathione Can Compensate for Salicylic Acid Deficiency in Tobacco to Maintain Resistance toFrontiers in plant science · 2019Article
- The Defense Response ofViruses · 2018Article
- Glutathione S-Transferase Enzymes in Plant-Pathogen Interactions.Frontiers in plant science · 2018Review
- Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCapsicum chlorosis virus (CaCV) is an emerging pathogen of capsicum, tomato and peanut crops in Australia and South-East Asia. Commercial capsicum cultivars with CaCV resistance are not yet available, but CaCV resistance identified in Capsicum chinense is being introgressed into commercial Bell capsicum. However, our knowledge of the molecular mechanisms leading to the resistance response to CaCV infection is limited. Therefore, transcriptome and expression profiling data provide an important resource to better understand CaCV resistance mechanisms. METHODOLOGY/PRINCIPAL
findingsWe assembled capsicum transcriptomes and analysed gene expression using Illumina HiSeq platform combined with a tag-based digital gene expression system. Total RNA extracted from CaCV/mock inoculated CaCV resistant (R) and susceptible (S) capsicum at the time point when R line showed a strong hypersensitive response to CaCV infection was used in transcriptome assembly. Gene expression profiles of R and S capsicum in CaCV- and buffer-inoculated conditions were compared. None of the genes were differentially expressed (DE) between R and S cultivars when mock-inoculated, while 2484 genes were DE when inoculated with CaCV. Functional classification revealed that the most highly up-regulated DE genes in R capsicum included pathogenesis-related genes, cell death-associated genes, genes associated with hormone-mediated signalling pathways and genes encoding enzymes involved in synthesis of defense-related secondary metabolites. We selected 15 genes to confirm DE expression levels by real-time quantitative PCR. CONCLUSION/SIGNIFICANCE: DE transcript profiling data provided comprehensive gene expression information to gain an understanding of the underlying CaCV resistance mechanisms. Further, we identified candidate CaCV resistance genes in the CaCV-resistant C. annuum x C. chinense breeding line. This knowledge will be useful in future for fine mapping of the CaCV resistance locus and potential genetic engineering of resistance into CaCV-susceptible crops.
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