Evidence map›Paper›PMID 27398402›Full record

ArticleACS biomaterials science & engineering2015

Silk-Its Mysteries, How It Is Made, and How It Is Used.

Davoud Ebrahimi, Olena Tokareva, Nae Gyune Rim, Joyce Y Wong, David L Kaplan, Markus J Buehler

Abstract read
In one paragraph

Article in ACS biomaterials science & engineering, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Pollen-inspired biopolymer-based multifunctional films.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Sonification basedAPL bioengineering · 2020
    Article
  14. Chemical Synthesis of Silk-Mimetic Polymers.Materials (Basel, Switzerland) · 2019
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Imaging and analysis of a three-dimensional spider web architecture.Journal of the Royal Society, Interface · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Davoud EbrahimiLaboratory for Atomistic and Molecular Mechanics, Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.
Olena TokarevaLaboratory for Atomistic and Molecular Mechanics, Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States; Department of Biomedical Engineering, Tufts University, Medford, Massachusetts 02155, United States.
Nae Gyune RimDepartment of Biomedical Engineering, Boston University, Boston, Massachusetts 02215, United States.
Joyce Y WongDepartment of Biomedical Engineering, Boston University, Boston, Massachusetts 02215, United States; Division of Materials Science and Engineering, Boston University, Boston, Massachusetts 02215, United States.
David L KaplanDepartment of Biomedical Engineering, Tufts University, Medford, Massachusetts 02155, United States.
Markus J BuehlerLaboratory for Atomistic and Molecular Mechanics, Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.

Funding

Models to Predict Protein Biomaterial PerformanceU01EB014976 · NIBIB · TUFTS UNIVERSITY MEDFORD · PI BUEHLER, MARKUS J., KAPLAN, DAVID L. · 2012 to 2020
$5.2M
NIBIB NIH HHS U01 EB014976
6 · The paper itself

Abstract

This article reviews fundamental and applied aspects of silk-one of Nature's most intriguing materials in terms of its strength, toughness, and biological role-in its various forms, from protein molecules to webs and cocoons, in the context of mechanical and biological properties. A central question that will be explored is how the bridging of scales and the emergence of hierarchical structures are critical elements in achieving novel material properties, and how this knowledge can be explored in the design of synthetic materials. We review how the function of a material system at the macroscale can be derived from the interplay of fundamental molecular building blocks. Moreover, guidelines and approaches to current experimental and computational designs in the field of synthetic silklike materials are provided to assist the materials science community in engineering customized finetuned biomaterials for biomedical applications.

Indexed as

biomimeticmateriomicsmultiscale modelingsilkspinning

Identifiers

PMID27398402
PMCPMC4936833

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.