ReviewIranian journal of public health2016
Hyperbilirubinemia in Neonates: Types, Causes, Clinical Examinations, Preventive Measures and Treatments: A Narrative Review Article.
Review in Iranian journal of public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
72 citing papers in PubMed, 4 syntheses or guidelines pooled it, 206 citations in OpenAlex.
- Association of SLCO1B1 genetic variants with neonatal hyperbilirubinemia: a consolidated analysis of 36 studies.BMC pediatrics · 2025Pooled it
- Role of ursodeoxycholic acid in neonatal indirect hyperbilirubinemia: a systematic review and meta-analysis of randomized controlled trials.Italian journal of pediatrics · 2022Pooled it
- Correlation between neonatal hyperbilirubinemia and vitamin D levels: A meta-analysis.PloS one · 2021Pooled it
- Etiology and therapeutic management of neonatal jaundice in Iran: a systematic review and meta-analysis.World journal of pediatrics : WJP · 2020Pooled it
- Effect of early skin-to-skin contact after vaginal birth on neonatal stress and day-5 bilirubin levels: a randomized trial.Scientific reports · 2026Trial
- Ursodeoxycholic Acid in the Management of Prolonged Neonatal Hyperbilirubinemia: A Randomized Controlled Clinical Trial.Iranian journal of medical sciences · 2026Trial
- Trial
- A randomized control trial of phototherapy and 20% albumin versus phototherapy and saline in Kilifi, Kenya.BMC research notes · 2019Trial
- Impact of altered heme oxygenase-1 in caring for preterm neonates: navigating the unknown.Pediatric research · 2026Review
- A novel medical device that combines filtered sunlight phototherapy and kangaroo care to treat neonatal jaundice: bench feasibility study.Pediatric research · 2026Article
- Optimising Formulations for Paediatric Patients with Inherited Metabolic Disorders: The Case Study of Levocarnitine.Pharmaceutical medicine · 2026Review
- The connection between neonatal jaundice and neurodevelopment later in life: a national birth cohort study.BMC public health · 2026Article
- A 10-year retrospective assessment of prevalence and factors associated with jaundice among neonates in selected facilities in Ondo State.BMC pediatrics · 2026Article
- Treatment outcome of neonatal jaundice and its predictors among neonates admitted at NICU in Bahir Dar city public hospitals: a multi-center retrospective follow-up study.BMC pediatrics · 2026Article
- Article
- Incidence and risk factors for neonatal jaundice in a teaching hospital in Northern Ghana.BMC pediatrics · 2025Article
- Diagnosing acute bilirubin encephalopathy in neonates using MRI-based deep learning model.BMC pediatrics · 2025Article
- Article
- Bilisense: An affordable sensor for on-site diagnosis of jaundice and prevention of kernicterus.Biosensors & bioelectronics · 2025Article
- Protective role of alcoholic extract ofOpen veterinary journal · 2025Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHyperbilirubinemia, or jaundice, is a life threatening disorder in newborns. It is a multifactorial disorder with many symptoms. Generally, the physiological jaundice is the most prevalent type however in some regions pathological jaundice is also common. This review article focuses on a brief introduction to jaundice, its types and causes, measuring the bilirubin level, clinical approaches towards hyperbilirubinemia, different precautionary measures for the parents of babies suffering from hyperbilirubinemia and different remedial therapeutic measures for its treatment.
methodsThe main databases including Scopus, Pubmed, MEDLINE, Google scholar and Science Direct were researched to obtain the original papers related to the newborns' hyperbilirubinemia. The main terms used to literature search were "newborns' hyperbilirubinemia", "newborns' jaundice", "Physiological Jaundice" and "Patholigical Jaundice". The timeframe included the obtained articles was from 1952 to 2015.
resultsNeonatal jaundice due to breast milk feeding is also sometimes observed. Hemolytic jaundice occurs because of the incompatibility of blood groups with ABO and Rh factors, when the fetus and mother blood groups are not compatible and the fetus blood crosses the barrier of the umbilical cord before birth causing fetus blood hemolysis owing to severe immune response.
conclusionJaundice is easily diagnosable however require quick and on the spot treatment. If not treated properly, it leads to many complications. Currently the treatment options for jaundice include photo therapy, chemotherapy, and vaccinations.
Indexed as
Identifiers
27398328PMC4935699W2398905361What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.