Evidence map›Paper›PMID 27398317›Full record

ArticleFEBS open bio2016

Identification of lung-specific genes by meta-analysis of multiple tissue RNA-seq data.

Min Xiong, Daniel P Heruth, Li Qin Zhang, Shui Qing Ye

Open access · goldAbstract read
In one paragraph

Article in FEBS open bio, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Min XiongDivision of Experimental and Translational Genetics Department of Pediatrics The Children's Mercy Hospital University of Missouri Kansas City School of Medicine MO USA; Department of Biomedical and Health Informatics University of Missouri Kansas City School of Medicine MO USA.
Daniel P HeruthDivision of Experimental and Translational Genetics Department of Pediatrics The Children's Mercy Hospital University of Missouri Kansas City School of Medicine MO USA.
Li Qin ZhangDivision of Experimental and Translational Genetics Department of Pediatrics The Children's Mercy Hospital University of Missouri Kansas City School of Medicine MO USA.
Shui Qing YeDivision of Experimental and Translational Genetics Department of Pediatrics The Children's Mercy Hospital University of Missouri Kansas City School of Medicine MO USA; Department of Biomedical and Health Informatics University of Missouri Kansas City School of Medicine MO USA.
Children's Mercy Hospital · USMercy Hospital · USUniversity of Missouri Health System · USUniversity of Missouri–Kansas City · US

Funding

Novel Role of Pre-B-Cell Colony Enhancing Factor in ALIR01HL080042 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI YE, SHUI QING · 2006 to 2010
$1.8M
NHLBI NIH HHS R01 HL080042
6 · The paper itself

Abstract

Lung-specific genes play critically important roles in lung development, lung physiology, and pathogenesis of lung-associated diseases. We performed a meta-analysis of multiple tissue RNA-seq data to identify lung-specific genes in order to better investigate their lung-specific functions and pathological roles. We identified 83 lung-specific genes consisting of 62 protein-coding genes, five pseudogenes and 16 noncoding RNA genes. About 49.4% of lung-specific genes were implicated in the pathogenesis of lung diseases and 21.7% were involved with lung development. The identification of genes with enriched expression in the lung will facilitate the elucidation of lung-specific functions and their roles in disease pathogenesis.

Indexed as

genomelung‐associated diseaselung development geneslung‐specific genesRNA‐seq

Identifiers

PMID27398317
PMCPMC4932457
OpenAlexW2400877808

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.