ArticleSpringerPlus2016
Distant metastasis detected by routine staging in breast cancer patients participating in the national German screening programme: consequences for clinical practice.
Article in SpringerPlus, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Can Ki-67 serve as a suitable marker to indicate the necessity of staging diagnostics in cases of low-risk breast cancer?Archives of gynecology and obstetrics · 2025Article
- Clinical implications of non-breast cancer related findings on FDG-PET/CT scan prior to neoadjuvant chemotherapy in patients with breast cancer.Breast cancer research and treatment · 2024Article
- Diagnostic performance of additional imaging tests for staging purposes in a bicentric German series of low-risk early breast cancer patients.Archives of gynecology and obstetrics · 2024Article
- Is Metastatic Staging Needed for All Patients with Synchronous Bilateral Breast Cancers?Cancers · 2023Article
- Article
- Intensity of metastasis screening and survival outcomes in patients with breast cancer.Scientific reports · 2021Article
- Effect of Bone Reading CT software on radiologist performance in detecting bone metastases from breast cancer.The British journal of radiology · 2017Article
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Authors and funding
9 authors.
Funding
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Abstract
purposeTo determine frequency of routine radiological staging of breast cancer patients diagnosed in a German Breast Cancer Screening Center from 2007 to 2014, the incidence and consequences of distant metastases detected and the resulting implications for clinical routine.
methodsRecords of 896 patients with primary breast cancer diagnosed in the Screening Centre and treated in five participating hospitals were analyzed retrospectively. Evaluation included frequency and type of staging procedures and results with respect to distant metastasis and their consequences on clinical management.
results894/896 Patients (99.8 %) received staging for distant metastases by bone scintigraphy, chest X-ray and liver sonography and/or CT/MRT diagnostics. Distant metastasis was suggested In 6/894 patients but excluded in 3 by further diagnostics or clinical course. Thus, 3 (0.3 %) were clinically verified to have metastatic disease in bone (n = 2; both pT2) or in bone and lung (n = 1; cT4, cN3).
conclusionDue to the low incidence of verified metastatic disease, the high false positive rate of staging procedures and the unfavorable cost/benefit ratio routine radiological staging should be completely omitted in asymptomatic breast cancer patients diagnosed in a breast cancer screening programme.
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