Evidence map›Paper›PMID 27398217›Full record

ArticleBasic and clinical andrology2016

Is intracouple assisted reproductive technology an option for men with large-headed spermatozoa? A literature review and a decision guide proposal.

Bruno Guthauser, Xavier Pollet-Villard, Florence Boitrelle, Francois Vialard

Abstract read
In one paragraph

Article in Basic and clinical andrology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bruno GuthauserLaboratoire de Biologie de la Reproduction, Hôpital Tenon, Paris, France.
Xavier Pollet-VillardCentre d'AMP Nataliance, Laboratoire Medibio, Saran, France.
Florence BoitrelleGIG, EA7404, Université Versailles St Quentin en Yvelines, Montigny le Bretonneux, France ; Unité de Biologie de la Reproduction, CHI de Poissy St Germain, Poissy, France.
Francois VialardGIG, EA7404, Université Versailles St Quentin en Yvelines, Montigny le Bretonneux, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the presence of spermatozoa with an abnormally large head is rare, it is associated with low fertility or even total infertility. We reviewed the literature on assisted reproductive technology (ART) strategies and outcomes for men with large-headed spermatozoa. We also discuss additional analyses that can usefully characterize sperm defects and help with the choice between intra-couple ART and insemination with donor sperm. Lastly, we propose a classification for cases of large-headed spermatozoa.

Indexed as

Assisted reproductive technology outcomesFluorescence in situ hybridizationLarge-headed spermatozoaMacrocephalic sperm head syndromeSperm head measurement

Identifiers

PMID27398217
PMCPMC4939046

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.