Evidence map›Paper›PMID 27397480›Full record

SynthesisInfluenza and other respiratory viruses2016

A systematic review of factors affecting intended and actual adherence with antiviral medication as treatment or prophylaxis in seasonal and pandemic flu.

Louise E Smith, Donatella D'Antoni, Vageesh Jain, Julia M Pearce, John Weinman, G James Rubin

Registry-linked trialOpen access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Influenza and other respiratory viruses, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03431012 (Improving Communication During a Pandemic Flu Outbreak), which is not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03431012 nacompletednot on this map

Improving Communication During a Pandemic Flu Outbreak

TypeinterventionalSponsorKing's College LondonRan2016 to 2016Enrolled349ConditionsHealthyArmsAgency Assignment framing, Attribute framing
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Guideline-Concordant Antiviral Treatment in Children at High Risk for Influenza Complications.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Louise E SmithDepartment of Psychological Medicine, King's College London, London, UK.ORCID 0000-0002-1277-2564
Donatella D'AntoniInstitute of Pharmaceutical Science, King's College London, London, UK.
Vageesh JainDepartment of Psychological Medicine, King's College London, London, UK.
Julia M PearceDepartment of War Studies, King's College London, London, UK.
John WeinmanInstitute of Pharmaceutical Science, King's College London, London, UK.
G James RubinDepartment of Psychological Medicine, King's College London, London, UK. Gideon.rubin@kcl.ac.uk.
King's College London · GB

Funding

Department of Health
6 · The paper itself

Abstract

The aim of this review was to identify factors predicting actual or intended adherence to antivirals as treatment or prophylaxis for influenza. Literature from inception to March 2015 was systematically reviewed to find studies reporting predictors of adherence to antivirals and self-reported reasons for non-adherence to antivirals. Twenty-six studies were included in the review; twenty identified through the literature search and six through other means. Of these studies, 18 assessed predictors of actual adherence to antivirals, whereas eight assessed predictors of intended adherence. The most commonly found predictor of, and self-reported reason for, non-adherence was the occurrence of side effects. Other predictors include perceptions surrounding self-efficacy, response efficacy and perceived personal consequences as well as social influences of others' experiences of taking antivirals. Predictors identified in this review can be used to help inform communications to increase adherence to antivirals in both seasonal and pandemic influenza.

Indexed as

Medication AdherenceAntiviral AgentsDisease OutbreaksHumansInfluenza A Virus, H1N1 SubtypeInfluenza, HumanPandemicsSeasonsAntiviral Agentsadherenceantiviralsinfluenzapandemic

Identifiers

PMID27397480
PMCPMC5059947
OpenAlexW2468650733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.