Evidence map›Paper›PMID 27396693›Full record

ArticleAutonomic neuroscience : basic & clinical2017

Role of the abdominal vagus and hindbrain in inhalational anesthesia-induced vomiting.

Ragini G Gupta, Claire Schafer, Yolande Ramaroson, Michael G Sciullo, Charles C Horn

Open access · greenAbstract read
In one paragraph

Article in Autonomic neuroscience : basic & clinical, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Observational
  6. Article
  7. Article
  8. The effect of isoflurane onEJNMMI research · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Ragini G GuptaUniversity of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Claire SchaferDepartment of Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA.
Yolande RamarosonAgroSup, Dijon, France.
Michael G SciulloBiobehavioral Oncology Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA.
Charles C HornUniversity of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Biobehavioral Oncology Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA; Department of Anesthesiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Medicine, Division of Gastroenterology, Hepatology, and Nutrition, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, United States. Electronic address: chorn@pitt.edu.
University of Pittsburgh · USInstitut Agro Dijon · FRUPMC Hillman Cancer Center · US

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Jessie Nedrow · 1988 to 2026
$158.0M
NCI NIH HHS P30 CA047904
6 · The paper itself

Abstract

The incidence of postoperative nausea and vomiting (PONV) can be as high as 80% in patients with risk factors (e.g., females, history of motion sickness). PONV delays postoperative recovery and costs several hundred million dollars annually. Cell-based assays show that halogenated ethers (e.g., isoflurane) activate 5-HT

Indexed as

Anesthesia, InhalationAnesthetics, InhalationAnimalsDose-Response Relationship, DrugEmeticsFemaleImmunohistochemistryIsofluraneModels, AnimalNeural PathwaysProto-Oncogene Proteins c-fosRandom AllocationRhombencephalonShrewsStilbamidinesVagotomy2-hydroxy-4,4'-diamidinostilbene, methanesulfonate saltAnesthetics, InhalationEmeticsIsofluraneProto-Oncogene Proteins c-fosStilbamidinesAnesthesiologyIsofluraneNTSPerioperative carePost-anesthesia care unitPost-operative nausea and vomiting

Identifiers

PMID27396693
PMCPMC5203944
OpenAlexW2464741884

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.