Evidence map›Paper›PMID 27396513›Full record

ArticleTrends in molecular medicine2016

Our Mothers' Antibodies as Guardians of our Commensals.

Stephanie C Ganal-Vonarburg, Andrew J Macpherson

Abstract readComment
PubMed Publisher
In one paragraph

Article in Trends in molecular medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Stephanie C Ganal-VonarburgMaurice Müller Laboratories (DKF), Universitätsklinik für Viszerale Chirurgie und Medizin, Inselspital, Murtenstrasse 35, University of Bern, 3010 Bern, Switzerland. Electronic address: stephanie.ganal@dkf.unibe.ch.
Andrew J MacphersonMaurice Müller Laboratories (DKF), Universitätsklinik für Viszerale Chirurgie und Medizin, Inselspital, Murtenstrasse 35, University of Bern, 3010 Bern, Switzerland. Electronic address: andrew.macpherson@dkf.unibe.ch.
University Hospital of Bern · CHUniversity of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucosal secretory IgA protects the mammalian body from invasion of commensal bacteria colonizing the intestine. A recent murine study in Cell shows that commensal-specific antibodies of the IgG isotype are also present in the serum and that maternal commensal-specific IgA and IgG are crucial for maintaining host-microbe mutualism in the offspring.

Indexed as

AnimalsAnimals, NewbornFemaleImmunityImmunoglobulin A, SecretoryImmunoglobulin GIntestinesLactationMiceMilkPregnancySymbiosisImmunoglobulin A, SecretoryImmunoglobulin G

Identifiers

PMID27396513
OpenAlexW2475131742

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.