Evidence map›Paper›PMID 27396476›Full record

ArticleContrast media & molecular imaging2016

Uptake and retention of manganese contrast agents for PET and MRI in the rodent brain.

Christina L Brunnquell, Reinier Hernandez, Stephen A Graves, Ivy Smit-Oistad, Robert J Nickles, Weibo Cai, M Elizabeth Meyerand, Masatoshi Suzuki

Open access · bronzeAbstract read
In one paragraph

Article in Contrast media & molecular imaging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Manganese-Enhanced MRI of the Brain in Healthy Volunteers.AJNR. American journal of neuroradiology · 2019
    Article
  6. Manganese in PET imaging: Opportunities and challenges.Journal of labelled compounds & radiopharmaceuticals · 2019
    Review
  7. Article
  8. Article
  9. PET radiometals for antibody labeling.Journal of labelled compounds & radiopharmaceuticals · 2018
    Review
  10. Review
  11. Article
  12. Article
  13. Nuclear excitation functions of proton-induced reactions (ENuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms · 2016
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Christina L BrunnquellDepartment of Medical Physics, University of Wisconsin-Madison, Madison, WI, USA.
Reinier HernandezDepartment of Medical Physics, University of Wisconsin-Madison, Madison, WI, USA.
Stephen A GravesDepartment of Medical Physics, University of Wisconsin-Madison, Madison, WI, USA.
Ivy Smit-OistadDepartment of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI, USA.
Robert J NicklesDepartment of Medical Physics, University of Wisconsin-Madison, Madison, WI, USA.
Weibo CaiDepartment of Medical Physics, University of Wisconsin-Madison, Madison, WI, USA.
M Elizabeth MeyerandDepartment of Medical Physics, University of Wisconsin-Madison, Madison, WI, USA. memeyerand@wisc.edu.
Masatoshi SuzukiDepartment of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI, USA. masatoshi.suzuki@wisc.edu.
University of Wisconsin–Madison · US

Funding

Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
BIOTECHNOLOGY TRAINING PROGRAMT32GM008349 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI FOX, BRIAN G · 1989 to 2019
$22.5M
U.W. RADIOLOGICAL SCIENCES TRAINING PROGRAMT32CA009206 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Bryan Patrick Bednarz · 1985 to 2026
$12.1M
Muscle stem cells: New ALS growth factor therapy and disease modelR01NS091540 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI SUZUKI, MASATOSHI · 2015 to 2019
$1.7M
NCATS NIH HHS UL1 TR000427NCI NIH HHS T32 CA009206NIGMS NIH HHS T32 GM008349NINDS NIH HHS R01 NS091540
6 · The paper itself

Abstract

Manganese-enhanced magnetic resonance imaging (MRI) is an established neuroimaging method for signal enhancement, tract tracing, and functional studies in rodents. Along with the increasing availability of combined positron emission tomography (PET) and MRI scanners, the recent development of the positron-emitting isotope

Indexed as

AnimalsBrainChloridesContrast MediaMagnetic Resonance ImagingManganeseManganese CompoundsMultimodal ImagingNeuroimagingPositron-Emission TomographyRadioisotopesRatsTissue DistributionChloridesContrast MediaManganesemanganese chlorideManganese CompoundsRadioisotopesmanganesemanganese-enhanced magnetic resonance imaging (MEMRI)neuroimagingpositron emission tomography (PET)quantitative imaging

Identifiers

PMID27396476
PMCPMC5140672
OpenAlexW2511315799

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.