Evidence map›Paper›PMID 27395776›Full record

ArticleThe ocular surface2016

Evaporation and Hydrocarbon Chain Conformation of Surface Lipid Films.

Samiyyah M Sledge, Hussain Khimji, Douglas Borchman, Alexandria L Oliver, Heidi Michael, Emily K Dennis, Dylan Gerlach, Rahul Bhola, Elsa Stephen

Abstract read
In one paragraph

Article in The ocular surface, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Effect of Model Tear Film Lipid Layer on Water Evaporation.Investigative ophthalmology & visual science · 2023
    Article
  7. Review
  8. In Vitro Inhibition of Evaporation with Perfluorohexyloctane, an Eye Drop for Dry Eye Disease.Current therapeutic research, clinical and experimental · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. New approaches for diagnosis of dry eye disease.International journal of ophthalmology · 2019
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Samiyyah M SledgeDepartment of Ophthalmology and Visual Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Hussain KhimjiDepartment of Ophthalmology and Visual Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Douglas BorchmanDepartment of Ophthalmology and Visual Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA. Electronic address: borchman@louisville.edu.
Alexandria L OliverDepartment of Ophthalmology and Visual Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Heidi MichaelDepartment of Ophthalmology and Visual Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Emily K DennisDepartment of Ophthalmology and Visual Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Dylan GerlachDepartment of Ophthalmology and Visual Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Rahul BholaDepartment of Ophthalmology and Visual Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Elsa StephenDepartment of Ophthalmology and Visual Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA.

Funding

Tear Film Lipid Compositional, Structural, Functional, Relationships, and Dry EyeR01EY026180 · NEI · UNIVERSITY OF LOUISVILLE · PI BORCHMAN, DOUGLAS · 2016 to 2020
$1.4M
NEI NIH HHS R01 EY026180
6 · The paper itself

Abstract

purposeThe inhibition of the rate of evaporation (R

methodsR

resultsThe Raman scattering intensity of the lipid film deviated by about 7 % for hydroxyl lipids and varied by 21 % for meibum films across the entire film at a resolution of 5 μm

conclusionsHuman meibum and hydroxyl lipids, regardless of their fluidity, chain length, or thickness did not inhibit R

Indexed as

AdultChildChild, PreschoolEye ProteinsFemaleHumansHydrocarbonsHydroxidesLipidsMaleMeibomian GlandsMiddle AgedSpectrum Analysis, RamanSurface PropertiesTearsVolatilizationEye ProteinsHydrocarbonshydroxide ionHydroxidesLipidstear proteinsdry eyehydroxyl lipidsmeibumtear evaporationtear film lipid layer

Identifiers

PMID27395776
PMCPMC5065757

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.