ArticleMolecular ecology2016
The genomewide transcriptional response underlying the pea aphid wing polyphenism.
Article in Molecular ecology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
32 citing papers in PubMed, 78 citations in OpenAlex.
- Reduction of Buchnera with rifampicin impairs the density-dependent induction of winged morph in pea aphid.Insect science · 2026Article
- Aphid wing plasticity: hormonal and epigenetic control mechanisms.Current opinion in insect science · 2026Review
- Behavioral and physiological responses of the aphelinid parasitoid, Encarsia formosa, to interspecific competitors.Communications biology · 2025Article
- The maternal vGluT2 and embryonic mGluR3 signaling relay system controls offspring wing dimorphism in pea aphid.iScience · 2025Article
- A-to-I RNA editing ofeLife · 2025Article
- Wing Plasticity Is Associated with Growth and Energy Metabolism in Two Color Morphs of the Pea Aphid.Insects · 2024Article
- Evolution and molecular mechanisms of wing plasticity in aphids.Current opinion in insect science · 2024Review
- Dopamine mediates the pea aphid wing plasticity.Biology letters · 2023Article
- One genome, multiple phenotypes: decoding the evolution and mechanisms of environmentally induced developmental plasticity in insects.Biochemical Society transactions · 2023Review
- Identification and Expression Analysis of Chemosensory Genes in the Antennal Transcriptome of Chrysanthemum AphidInsects · 2022Article
- miR-92a-1-p5 Modulated Expression of the flightin Gene Regulates Flight Muscle Formation and Wing Extension in the Pea Aphid, Acyrthosiphon pisum (Hemiptera: Aphidoidea).Journal of insect science (Online) · 2022Article
- Insights Into Chemosensory Proteins From Non-Model Insects: Advances and Perspectives in the Context of Pest Management.Frontiers in physiology · 2022Review
- Secondary Symbionts Affect Foraging Capacities of Plant-Specialized Genotypes of the Pea Aphid.Microbial ecology · 2021Article
- Contribution of Epigenetic Mechanisms in the Regulation of Environmentally-Induced Polyphenism in Insects.Insects · 2021Review
- Identification and Analysis of MicroRNAs Associated with Wing Polyphenism in the Brown Planthopper,International journal of molecular sciences · 2020Article
- Selection following Gene Duplication Shapes Recent Genome Evolution in the Pea Aphid Acyrthosiphon pisum.Molecular biology and evolution · 2020Article
- Expression profiling of winged- and wingless-destined pea aphid embryos implicates insulin/insulin growth factor signaling in morph differences.Evolution & development · 2020Article
- Differences in Cell Proliferation and Craniofacial Phenotype of Closely Related Species in the Pupfish Genus Cyprinodon.The Journal of heredity · 2020Article
- miR-147b-modulated expression of vestigial regulates wing development in the bird cherry-oat aphid Rhopalosiphum padi.BMC genomics · 2020Article
- Variation in intrinsic resistance of pea aphids to parasitoid wasps: A transcriptomic basis.PloS one · 2020Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Phenotypic plasticity is a key life history strategy used by many plants and animals living in heterogeneous environments. A multitude of studies have investigated the costs and limits of plasticity, as well as the conditions under which it evolves. Much less well understood are the molecular genetic mechanisms that enable an organism to sense its environment and respond in a plastic manner. The pea aphid wing polyphenism is a compelling laboratory model to study these mechanisms. In this polyphenism, environmental stressors like high density cause asexual, viviparous adult female aphids to change the development of their embryos from wingless to winged morphs. The life history trade-offs between the two morphs have been intensively studied, but the molecular mechanisms underlying this process remain largely unknown. We therefore performed a genomewide study of the maternal transcriptome at two time points with and without a crowding stress to discover the maternal molecular changes that lead to the development of winged vs. wingless offspring. We observed significant transcriptional changes in genes associated with odorant binding, neurotransmitter transport, hormonal activity and chromatin remodelling in the maternal transcriptome. We also found that titres of serotonin, dopamine and octopamine were higher in solitary compared to crowded aphids. We use these results to posit a model for how maternal signals inform a developing embryo to be winged or wingless. Our findings add significant insights into the identity of the molecular mechanisms that underlie environmentally induced morph determination and suggest a possible role for biogenic amine regulation in polyphenisms generally.
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