Evidence map›Paper›PMID 27393215›Full record

ArticleThe Journal of physiology2017

Serotonin controls initiation of locomotion and afferent modulation of coordination via 5-HT

Anna M Cabaj, Henryk Majczyński, Erika Couto, Phillip F Gardiner, Katinka Stecina, Urszula Sławińska, Larry M Jordan

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 58 citations in OpenAlex.

  1. Bioamine disruption leads to memory deficits in the whip spider, Phrynus marginemaculatus.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026
    Article
  2. Article
  3. Article
  4. Circuit Reconstruction after Traumatic Spinal Cord Injury by Cellular and Pharmacological Approaches.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Serotonergic Facilitation of Forelimb Functional Recovery in Rats with Cervical Spinal Cord Injury.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021
    Article
  12. Article
  13. Article
  14. Spike-induced ordering: Stochastic neural spikes provide immediate adaptability to the sensorimotor system.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  15. Article
  16. Article
  17. Contribution of 5-HTFrontiers in neural circuits · 2020
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Anna M CabajDepartment of Neurophysiology, Nencki Institute of Experimental Biology PAS, 02-093, Warsaw, Poland.
Henryk MajczyńskiDepartment of Neurophysiology, Nencki Institute of Experimental Biology PAS, 02-093, Warsaw, Poland.
Erika CoutoDepartment of Physiology & Pathophysiology, Spinal Cord Research Centre, University of Manitoba, Winnipeg, MB, R3E 0J9, Canada.
Phillip F GardinerDepartment of Physiology & Pathophysiology, Spinal Cord Research Centre, University of Manitoba, Winnipeg, MB, R3E 0J9, Canada.
Katinka StecinaDepartment of Physiology & Pathophysiology, Spinal Cord Research Centre, University of Manitoba, Winnipeg, MB, R3E 0J9, Canada.
Urszula SławińskaDepartment of Neurophysiology, Nencki Institute of Experimental Biology PAS, 02-093, Warsaw, Poland.
Larry M JordanDepartment of Physiology & Pathophysiology, Spinal Cord Research Centre, University of Manitoba, Winnipeg, MB, R3E 0J9, Canada.ORCID 0000-0003-2501-4276
Research Manitoba · CAInstytut Biologii Doświadczalnej im. Marcelego Nenckiego · PL

Funding

Canadian Institutes of Health Research CIHR 115147Canadian Institutes of Health Research CIHR 84250
6 · The paper itself

Abstract

key pointsExperiments on neonatal rodent spinal cord showed that serotonin (5-HT), acting via 5-HT ABSTRACT: Serotonergic pathways to the spinal cord are implicated in the control of locomotion based on studies using serotonin type 7 (5-HT

Indexed as

AnimalsElectric StimulationFemaleHindlimbLocomotionMotor NeuronsMuscle, SkeletalPhenolsRats, Sprague-DawleyRats, WistarReceptors, SerotoninReflexSerotoninSerotonin AntagonistsSpinal CordSulfonamidesPhenolsReceptors, SerotoninSB 269970Serotoninserotonin 7 receptorSerotonin AntagonistsSulfonamidesfictive locomotionserotoninvoluntary locomotion

Identifiers

PMID27393215
PMCPMC5199736
OpenAlexW2460483057

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.