Evidence map›Paper›PMID 27392903›Full record

ArticleInternational journal of behavioral medicine2016

Pre-Existing Diabetes in Early Stage Breast Cancer Patients is Associated with Lack of Improvement in Quality of Life 2 Years After Diagnosis.

Soghra Jarvandi, Maria Pérez, Mario Schootman, Donna B Jeffe

Abstract read
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In one paragraph

Article in International journal of behavioral medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Utility values and its time to deterioration in breast cancer patients after diagnosis and during treatments.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Soghra JarvandiDepartment of Family and Consumer Sciences, University of Tennessee, Knoxville, TN, 37996, USA. sjarvand@utk.edu.
Maria PérezDepartment of Internal Medicine, Washington University School of Medicine, Saint Louis, MO, 63110, USA.
Mario SchootmanCollege for Public Health and Social Justice, Saint Louis University, Saint Louis, MO, 63104, USA.
Donna B JeffeDepartment of Internal Medicine, Washington University School of Medicine, Saint Louis, MO, 63110, USA.
Barnes-Jewish Hospital · USUniversity of Tennessee at Knoxville · USWashington University in St. Louis · US

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI Joel Richard Garbow · 2001 to 2026
$128.0M
Quality of Life Over Time: DCIS vs Early Breast CancerR01CA102777 · NCI · WASHINGTON UNIVERSITY · PI JEFFE, DONNA B · 2003 to 2007
$1.5M
NCI NIH HHS P30 CA091842NCI NIH HHS R01 CA102777
6 · The paper itself

Abstract

purposeType 2 diabetes is a common comorbidity among breast cancer survivors. Our aim was to assess the association between diabetes and quality of life (QOL) in newly diagnosed early stage (0-IIA) breast cancer patients over a 2-year follow-up.

methodsWe used data from a longitudinal study of 549 breast cancer patients, aged ≥40 years. During four telephone interviews administered 4-6 weeks and 6, 12, and 24 months after definitive surgical treatment, we measured QOL using the Functional Assessment of Cancer Therapy-Breast (FACT-B) scale; higher scores indicate better QOL. Repeated measures analysis of variance was used to test the change over time in total FACT-B and each of the five subscales (physical, social, emotional and functional well-being, and breast cancer concerns), comparing patients with and without diabetes at baseline.

resultsAfter adjusting for covariates (age, race, body mass index, education, marital status, cancer staging, and surgical side effects), patients with (vs. without) diabetes reported lower QOL over time on the total FACT-B (least-squares mean [standard error] 106.2 [2.1] vs. 112.0 [1.1]; p = 0.0038) and on physical, social, emotional, and functional well-being subscales (each p < 0.05). Over the 2-year follow-up, QOL improved significantly for the emotional well-being (p < 0.0001) and breast cancer concern subscales (p = 0.0282) among patients without diabetes, but not among patients with diabetes.

conclusionEarly stage breast cancer patients with diabetes may need additional care considerations to improve QOL.

Indexed as

Quality of LifeSurvivorsBreast NeoplasmsComorbidityDiabetes Mellitus, Type 2EmotionsFemaleHumansLongitudinal StudiesMiddle AgedBreast cancerCohort studyDiabetesFunctional Assessment of Cancer Therapy-Breast (FACT-B)Quality of lifeSurgical side effects

Identifiers

PMID27392903
PMCPMC5121030
OpenAlexW2464186327

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.