Evidence map›Paper›PMID 27392778›Full record

ArticleInternational journal of colorectal disease2016

Risk factors for clinical anastomotic leakage after right hemicolectomy.

Mikkel Jessen, Malene Nerstrøm, Therese Emilie Wilbek, Søren Roepstorff, Morten S Rasmussen, Peter-Martin Krarup

Abstract read
PubMed Publisher
In one paragraph

Article in International journal of colorectal disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Observational
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mikkel JessenDigestive Disease Centre, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Malene NerstrømDigestive Disease Centre, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Therese Emilie WilbekDigestive Disease Centre, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Søren RoepstorffDigestive Disease Centre, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Morten S RasmussenDigestive Disease Centre, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Peter-Martin KrarupDigestive Disease Centre, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark. krarup75@gmail.com.ORCID http://orcid.org/0000-0003-1319-1451
University of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAnastomotic leakage (AL) after right hemicolectomy is a devastating complication, and risk factors for AL in this setting are rarely investigated exclusively. Recent reports suggest that anastomotic type may influence the rate of AL in ileocolic anastomoses. We investigated risk factors and short-term outcomes in patients subjected to right hemicolectomy.

methodsData from all patients undergoing right hemicolectomy at our institution between 2009 and 2013 were collected in a database. Risk factors for clinical AL, 30-day mortality, hospital and intensive care unit stay were investigated. Stepwise logistic regression was used to adjust for confounding.

results22/445 (4.9 %) patients had AL. Median time to AL was 6 days (range 2-11 days). A stapled anastomosis was associated with an increased AL rate compared with the handsewn approach (adjusted odds ratio (aOR) 2.84; 95 % CI 1.14-7.07; P = 0.025). Other risk factors for AL were tobacco use (aOR 2.70; 95 % CI 1.06-6.86; P = 0.037) and diabetes (aOR 5.95; 95 % CI 2.23-15.90; P < 0.001). Anastomotic ischemia was present in 6/13 stapled and 1/9 handsewn leaking anastomoses, P = 0.081, while generalized peritonitis was observed after 4/13 stapled and 7/9 handsewn leaking anastomoses, P = 0.030. Thirty-day mortality was 2/22 (9.1 %) in patients with AL and 23/423 (5.4 %) in patients without AL, P = 0.468, and 13/160 (8.1 %) and 12/285 (4.2 %), P = 0.085, in stapled and handsewn anastomoses, respectively.

conclusionsRisk factors for AL after right hemicolectomy were diabetes, tobacco use and stapled compared with handsewn anastomoses.

Indexed as

AgedAged, 80 and overAnastomosis, SurgicalAnastomotic LeakColectomyColonFemaleHumansIntraoperative CareLogistic ModelsMaleMultivariate AnalysisReoperationRisk FactorsAnastomotic leakageFunctional end-to-endRight hemicolectomyStapled anastomosis

Identifiers

PMID27392778
OpenAlexW2465581324

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.