Evidence map›Paper›PMID 27392754›Full record

ArticleAmerican journal of surgery2017

The changing pattern of diagnosing primary hyperparathyroidism in young patients.

Irene Lou, David F Schneider, Rebecca S Sippel, Herbert Chen, Dawn M Elfenbein

Open access · greenAbstract read
In one paragraph

Article in American journal of surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Two Different Causes of Paediatric Hypercalcaemia.Sultan Qaboos University medical journal · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Irene LouDepartment of Surgery, University of Wisconsin, 600 Highland Ave., K3/705 CSC, Madison, WI 53792, USA. Electronic address: lou@surgery.wisc.edu.
David F SchneiderDepartment of Surgery, University of Wisconsin, 600 Highland Ave., K3/705 CSC, Madison, WI 53792, USA.
Rebecca S SippelDepartment of Surgery, University of Wisconsin, 600 Highland Ave., K3/705 CSC, Madison, WI 53792, USA.
Herbert ChenDepartment of Surgery, University of Wisconsin, 600 Highland Ave., K3/705 CSC, Madison, WI 53792, USA; Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.
Dawn M ElfenbeinDepartment of Surgery, University of Wisconsin, 600 Highland Ave., K3/705 CSC, Madison, WI 53792, USA; Department of Surgery, University of California at Irvine, Orange, CA, USA.
University of Wisconsin–Madison · US

Funding

UW Surgical Oncology Research Training Program (UW-SORT)T32CA090217 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Muhammed Murtaza, Heather B Neuman · 2001 to 2026
$8.3M
Institutional Clinical and Translational Science AwardKL2TR000428 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$6.2M
NCATS NIH HHS KL2 TR000428NCI NIH HHS T32 CA090217
6 · The paper itself

Abstract

backgroundPrimary hyperparathyroidism (PHPT) is increasing in adults but rarely reported in young patients where routine blood work is obtained more judiciously. We aim to determine how PHPT is currently being diagnosed in young patients and examine surgical outcomes.

methodWe retrospectively analyzed PHPT patients 24 years of age or less who underwent parathyroidectomy from 2001 to 2014. Patients were divided into 2 time periods: 2001 to 2007 (A) and 2008 to 2014 (B). Incidentally, diagnosed patients lacked objective symptoms of PHPT and had no family history.

resultsForty young patients met inclusion criteria: 16 in group A and 24 in group B. Those in group A compared with group B had similar mean age, preoperative calcium, and parathyroid hormone (P > .05). Incidental diagnosis was more common in the contemporary group (42% vs 25%, P = .001).

conclusionsCurrent diagnosis of PHPT in young patients is increasingly incidental. This trend may be attributed to the more liberal use of labs in younger patients.

Indexed as

ParathyroidectomyAdolescentAge FactorsChildFemaleHumansHyperparathyroidism, PrimaryIncidental FindingsMaleRetrospective StudiesYoung AdultAdolescent hyperparathyroidismPediatric hyperparathyroidismPrimary hyperparathyroidism

Identifiers

PMID27392754
PMCPMC5154878
OpenAlexW2435609777

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.