Evidence map›Paper›PMID 27392677›Full record

SynthesisNeurosurgical review2018

Clinical and biomechanical researches of polyetheretherketone (PEEK) rods for semi-rigid lumbar fusion: a systematic review.

Chan Li, Lei Liu, Jian-Yong Shi, Kai-Zhong Yan, Wei-Zhong Shen, Zhen-Rong Yang

Abstract readComparative StudySystematic Review
PubMed Publisher
In one paragraph

Synthesis in Neurosurgical review, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

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  10. Satisfactory 2-year outcome of minimal invasive hybrid stabilization with double treated screws for unstable osteoporotic spinal fractures.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Article
  11. Article
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  19. Biomechanical analysis of lumbar interbody fusion supplemented with various posterior stabilization systems.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021
    Article
  20. Lumbar Fusion With Polyetheretherketone Rods Use for Patients With Degenerative Disease.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chan LiDepartment of Orthopedic Surgery (Spine Division), 1st People's Hospital of Taicang City, South Changshen Road 58#, Taicang, 215400, Jiangsu Province, China.
Lei LiuDivision of Rheumatology, Huashan Hospital, Shanghai Medical College, Fudan University, 12 Wulumuqizhong Road, 200040, Shanghai, China.
Jian-Yong ShiDepartment of Orthopedic Surgery (Spine Division), 1st People's Hospital of Taicang City, South Changshen Road 58#, Taicang, 215400, Jiangsu Province, China.
Kai-Zhong YanDepartment of Orthopedic Surgery (Spine Division), 1st People's Hospital of Taicang City, South Changshen Road 58#, Taicang, 215400, Jiangsu Province, China.
Wei-Zhong ShenDepartment of Orthopedic Surgery (Spine Division), 1st People's Hospital of Taicang City, South Changshen Road 58#, Taicang, 215400, Jiangsu Province, China.
Zhen-Rong YangDepartment of Orthopedic Surgery (Spine Division), 1st People's Hospital of Taicang City, South Changshen Road 58#, Taicang, 215400, Jiangsu Province, China. zryang@outlook.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lumbar spinal fusion using rigid rods is a common surgical technique. However, adjacent segment disease and other adverse effects can occur. Dynamic stabilization devices preserve physiologic motion and reduce painful stress but have a high rate of construct failure and reoperation. Polyetheretherketone (PEEK) rods for semi-rigid fusions have a similar stiffness and adequate stabilization power compared with titanium rods, but with improved load sharing and reduced mechanical failure. The purpose of this paper is to review and evaluate the clinical and biomechanical performance of PEEK rods. A systematic review of clinical and biomechanical studies was conducted. A literature search using the PubMed, EMBASE, and Cochrane Library databases identified studies that met the eligibility criteria. Eight clinical studies and 15 biomechanical studies were included in this systematic review. The visual analog scale and the Oswestry disability index improved significantly in most studies, with satisfactory fusion rates. The occurrence of adjacent segment disease was low. In biomechanical studies, PEEK rods demonstrated a superior load-sharing distribution, a larger adjacent segment range of motion, and reduced stress at the rod-screw/screw-bone interfaces compared with titanium rods. The PEEK rod construct was simple to assemble and had a reliable in vivo performance compared with dynamic devices. The quality of clinical studies was low with confounding results, although results from mechanical studies were encouraging. There is no evidence strong enough to confirm better outcomes with PEEK rods than titanium rods. More studies with better protocols, a larger sample size, and a longer follow-up time are needed.

Indexed as

KetonesPolyethylene GlycolsBenzophenonesBiomechanical PhenomenaBone ScrewsEquipment DesignFollow-Up StudiesHumansLumbar VertebraeOutcome and Process Assessment, Health CarePolymersSpinal FusionTitaniumBenzophenonesKetonespolyetheretherketonePolyethylene GlycolsPolymersTitaniumAdjacent segment diseaseFusion ratesPolyetheretherketone (PEEK) rodsSemi-rigid fusion

Identifiers

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.