ArticleEnvironmental science and pollution research international2016
Increased copper bioremediation ability of new transgenic and adapted Saccharomyces cerevisiae strains.
Article in Environmental science and pollution research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 45 citations in OpenAlex.
- Engineering Plant-Associated Microorganisms for Bioremediation and Sustainable Agriculture.Microorganisms · 2026Review
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- Physiological Response ofJournal of fungi (Basel, Switzerland) · 2022Article
- Bioreduction and bioremoval of hexavalent chromium by genetically engineered strains (Escherichia coli MT2A and Escherichia coli MT3).World journal of microbiology & biotechnology · 2022Article
- Microbial Interventions in Bioremediation of Heavy Metal Contaminants in Agroecosystem.Frontiers in microbiology · 2022Review
- Genetic circuit design automation for yeast.Nature microbiology · 2020Article
- Mineralization induced by phosphorylated dry baker's yeast.PloS one · 2020Article
- Microalgal Metallothioneins and Phytochelatins and Their Potential Use in Bioremediation.Frontiers in microbiology · 2020Review
- Recovering metals from aqueous solutions by biosorption onto phosphorylated dry baker's yeast.Scientific reports · 2019Article
- The biosorption of cadmium and cobalt and iron ions by yeast Cryptococcus humicola at nitrogen starvation.Folia microbiologica · 2018Article
- Heavy Metal Removal by Bioaccumulation Using Genetically Engineered Microorganisms.Frontiers in bioengineering and biotechnology · 2018Review
- Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Environmental pollution with heavy metals is a very serious ecological problem, which can be solved by bioremediation of metal ions by microorganisms. Yeast cells, especially Saccharomyces cerevisiae, are known to exhibit a good natural ability to remove heavy metal ions from an aqueous phase. In the present work, an attempt was made to increase the copper-binding properties of S. cerevisiae. For this purpose, new strains of S. cerevisiae were produced by construction and integration of recombinant human MT2 and GFP-hMT2 genes into yeast cells. The ySA4001 strain expressed GFP-hMT2p under the constitutive pADH1 promoter and the ySA4002 and ySA4003 strains expressed hMT2 and GFP-hMT2 under the inducible pCUP1 promoter. An additional yMNWTA01 strain was obtained by adaptation of the BY4743 wild type S. cerevisiae strain to high copper concentrations. The yMNWTA01, ySA4002, and ySA4003 strains exhibited an enhanced ability for copper ion bioremediation.
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Registered trials
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