Evidence map›Paper›PMID 27392075›Full record

ArticleAmerican journal of human genetics2016

Human Y Chromosome Haplogroup N: A Non-trivial Time-Resolved Phylogeography that Cuts across Language Families.

Anne-Mai Ilumäe, Maere Reidla, Marina Chukhryaeva, Mari Järve, Helen Post, Monika Karmin, Lauri Saag, Anastasiya Agdzhoyan, Alena Kushniarevich, Sergey Litvinov and 17 more

Abstract read
In one paragraph

Article in American journal of human genetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

  1. Article
  2. Article
  3. HLA Alleles and Haplotype Distribution Across Russian Population Groups.International journal of molecular sciences · 2026
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  7. Genetic history of Scythia.Science advances · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Anne-Mai IlumäeEstonian Biocentre and Department of Evolutionary Biology, University of Tartu, Tartu 51010, Estonia.
Maere ReidlaEstonian Biocentre and Department of Evolutionary Biology, University of Tartu, Tartu 51010, Estonia.
Marina ChukhryaevaVavilov Institute of General Genetics, Moscow 119991, Russia; Research Centre for Medical Genetics, Moscow 115478, Russia.
Mari JärveEstonian Biocentre and Department of Evolutionary Biology, University of Tartu, Tartu 51010, Estonia.
Helen PostEstonian Biocentre and Department of Evolutionary Biology, University of Tartu, Tartu 51010, Estonia.
Monika KarminEstonian Biocentre and Department of Evolutionary Biology, University of Tartu, Tartu 51010, Estonia.
Lauri SaagEstonian Biocentre and Department of Evolutionary Biology, University of Tartu, Tartu 51010, Estonia.
Anastasiya AgdzhoyanVavilov Institute of General Genetics, Moscow 119991, Russia.
Alena KushniarevichEstonian Biocentre and Department of Evolutionary Biology, University of Tartu, Tartu 51010, Estonia; Institute of Genetics and Cytology of the National Academy of Sciences of Belarus, Minsk 220072, Republic of Belarus.
Sergey LitvinovInstitute of Biochemistry and Genetics, Ufa Scientific Center, Russian Academy of Sciences, Ufa 450054, Russia; Estonian Biocentre and Department of Evolutionary Biology, University of Tartu, Tartu 51010, Estonia.
Natalya EkomasovaDepartment of Genetics and Fundamental Medicine, Bashkir State University, Ufa 450074, Russia.
Kristiina TambetsEstonian Biocentre and Department of Evolutionary Biology, University of Tartu, Tartu 51010, Estonia.
Ene MetspaluEstonian Biocentre and Department of Evolutionary Biology, University of Tartu, Tartu 51010, Estonia.
Rita KhusainovaInstitute of Biochemistry and Genetics, Ufa Scientific Center, Russian Academy of Sciences, Ufa 450054, Russia.
Bayazit YunusbayevEstonian Biocentre and Department of Evolutionary Biology, University of Tartu, Tartu 51010, Estonia.
Elza K KhusnutdinovaInstitute of Biochemistry and Genetics, Ufa Scientific Center, Russian Academy of Sciences, Ufa 450054, Russia; Department of Genetics and Fundamental Medicine, Bashkir State University, Ufa 450074, Russia.
Ludmila P OsipovaInstitute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia; Novosibirsk State University, Novosibirsk 630090, Russia.
Sardana FedorovaNorth-Eastern Federal University and Yakut Research Center of Complex Medical Problems, Yakutsk 677010, Sakha Republic, Russia.
Olga UtevskaV.N. Karazin Kharkiv National University, Kharkiv 61022, Ukraine.
Sergey KoshelFaculty of Geography, Lomonosov Moscow State University, Moscow 119991, Russia.
Elena BalanovskaResearch Centre for Medical Genetics, Moscow 115478, Russia.
Doron M BeharEstonian Biocentre and Department of Evolutionary Biology, University of Tartu, Tartu 51010, Estonia.
Oleg BalanovskyVavilov Institute of General Genetics, Moscow 119991, Russia; Research Centre for Medical Genetics, Moscow 115478, Russia.
Toomas KivisildEstonian Biocentre and Department of Evolutionary Biology, University of Tartu, Tartu 51010, Estonia; University of Cambridge, CB2 3QG Cambridge, UK.
Peter A UnderhillDepartment of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.
Richard VillemsEstonian Biocentre and Department of Evolutionary Biology, University of Tartu, Tartu 51010, Estonia; Estonian Academy of Sciences, Tallinn 10130, Estonia.
Siiri RootsiEstonian Biocentre and Department of Evolutionary Biology, University of Tartu, Tartu 51010, Estonia. Electronic address: sroots@ebc.ee.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The paternal haplogroup (hg) N is distributed from southeast Asia to eastern Europe. The demographic processes that have shaped the vast extent of this major Y chromosome lineage across numerous linguistically and autosomally divergent populations have previously been unresolved. On the basis of 94 high-coverage re-sequenced Y chromosomes, we establish and date a detailed hg N phylogeny. We evaluate geographic structure by using 16 distinguishing binary markers in 1,631 hg N Y chromosomes from a collection of 6,521 samples from 56 populations. The more southerly distributed sub-clade N4 emerged before N2a1 and N3, found mostly in the north, but the latter two display more elaborate branching patterns, indicative of regional contrasts in recent expansions. In particular, a number of prominent and well-defined clades with common N3a3'6 ancestry occur in regionally dissimilar northern Eurasian populations, indicating almost simultaneous regional diversification and expansion within the last 5,000 years. This patrilineal genetic affinity is decoupled from the associated higher degree of language diversity.

Indexed as

LanguageAsiaChromosomes, Human, YEuropeHaplotypesHumansPhylogeographyTime Factors

Identifiers

PMID27392075
PMCPMC5005449

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.