Evidence map›Paper›PMID 27392032›Full record

ArticlePloS one2016

The Fate of Patients with Solitary Pulmonary Nodules: Clinical Management and Radiation Exposure Associated.

Blanca Lumbreras, José Vilar, Isabel González-Álvarez, Noemí Gómez-Sáez, María L Domingo, María F Lorente, María Pastor-Valero, Ildefonso Hernández-Aguado

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 15 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Blanca LumbrerasPublic Health Department, Miguel Hernández University, Alicante, Spain.
José VilarRadiodiagnostic Department, Peset Hospital, Valencia, Spain.
Isabel González-ÁlvarezRadiodiagnostic Department, San Juan Hospital, Alicante, Spain.
Noemí Gómez-SáezPublic Health Department, Miguel Hernández University, Alicante, Spain.
María L DomingoRadiodiagnostic Department, Peset Hospital, Valencia, Spain.
María F LorenteRadiodiagnostic Department, San Juan Hospital, Alicante, Spain.
María Pastor-ValeroPublic Health Department, Miguel Hernández University, Alicante, Spain.
Ildefonso Hernández-AguadoPublic Health Department, Miguel Hernández University, Alicante, Spain.
Universitat de Miguel Hernández d'Elx · ESHospital Universitario Doctor Peset · ESHospital Universitari Sant Joan D'Alacant · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe appropriate management of the large number of lung nodules detected during the course of routine medical care presents a challenge. We aimed to evaluate the usual clinical practice in solitary pulmonary nodule (SPN) management and associated radiation exposure.

methodsWe examined 893 radiology reports of consecutive patients undergoing chest computed tomography (CT) and radiography at two public hospitals in Spain. Information on diagnostic procedures from SPN detection and lung cancer diagnosis was collected prospectively for 18 months.

resultsMore than 20% of patients with SPN detected on either chest radiograph (19.8%) or CT (26.1%) underwent no additional interventions and none developed lung cancer (100% negative predictive value). 346 (72.0%) patients with SPN detected on chest radiograph and 254 (61.5%) patients with SPN detected on CT had additional diagnostic tests and were not diagnosed with lung cancer. In patients undergoing follow-up imaging for SPNs detected on CT median number of additional imaging tests was 3.5 and the mean cumulative effective dose was 24.4 mSv; for those detected on chest radiograph the median number of additional imaging tests was 2.8 and the mean cumulative effective dose was 10.3 mSv.

conclusionsPatients who did not have additional interventions were not diagnosed of lung cancer. There was an excessive amount of interventions in a high percentage of patients presenting SPN, which was associated with an excess of radiation exposure.

Indexed as

LungAdultFemaleHumansLung NeoplasmsMalePositron-Emission TomographyRadiation ExposureSolitary Pulmonary NoduleThoraxTomography, X-Ray Computed

Identifiers

PMID27392032
PMCPMC4938621
OpenAlexW2470736009

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.