Trial reportAIDS care2016
Exploring the potential of a family-based prevention intervention to reduce alcohol use and violence within HIV-affected families in Rwanda.
Trial report in AIDS care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 8 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Gender-Based Violence Interventions in Low- and Middle-Income Countries: A Systematic Review of Interventions at Structural, Community, Interpersonal, Individual, and Multiple Levels.Trauma, violence & abuse · 2023Pooled it
- Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low- and middle-income countries.The Cochrane database of systematic reviews · 2023Pooled it
- Patient-level interventions to reduce alcohol-related harms in low- and middle-income countries: A systematic review and meta-summary.PLoS medicine · 2022Pooled it
- Culturally adapted evidence-based treatments for adults with substance use problems: A systematic review and meta-analysis.Drug and alcohol dependence · 2021Pooled it
- A Systematic Review of Household and Family Alcohol Use and Adolescent Behavioural Outcomes in Low- and Middle-Income Countries.Child psychiatry and human development · 2021Pooled it
- Psychosocial interventions for reducing alcohol consumption in sub-Saharan African settings: a systematic review and meta-analysis.Addiction (Abingdon, England) · 2021Pooled it
- Cognitive and Educational Interventions for Orphans and Vulnerable Children Affected by HIV/AIDS: A Meta-Analysis.Child development · 2021Pooled it
- A Systematic Review and Meta-Analysis of Interventions for Orphans and Vulnerable Children Affected by HIV/AIDS Worldwide.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2020Pooled it
- Risk and protective factors of depression among caregivers of children with disabilities in rural Rwanda.BMJ global health · 2026Trial
- Improved Relationship Quality, Equitable Gender Attitudes, and Reduced Alcohol Abuse as Key Mechanisms to Reduce Intimate Partner Violence in the Bandebereho Couples' Randomized Trial in Rwanda.Prevention science : the official journal of the Society for Prevention Research · 2022Trial
- Mediation pathways for reduced substance use among parents in South Africa: a randomized controlled trial.BMC public health · 2021Trial
- Family-based promotion of mental health in children affected by HIV: a pilot randomized controlled trial.Journal of child psychology and psychiatry, and allied disciplines · 2017Trial
- Strategies to integrate non-communicable disease interventions in HIV and tuberculosis care contexts in low- and middle-income countries: a scoping review.BMJ global health · 2026Article
- Improving family functioning and wellbeing among families of children with disabilities in Rwanda: an application of the SAFE child protection model.Frontiers in psychiatry · 2026Article
- Mental health and psychosocial support interventions for individuals affected by gender-based violence in fragile contexts: A systematic review.Global mental health (Cambridge, England) · 2026Review
- Integrating mental health care to reduce intimate partner violence in complex humanitarian emergencies.The Lancet. Global health · 2025Review
- Adaptation and validation of a Rwanda-focused version of the Alcohol Use Disorder Identification Test (AUDIT).PloS one · 2025Article
- Community-based models of care for adolescent and adult depression, suicidal behavior, anxiety, trauma, and substance use in Africa: a scoping review.Frontiers in psychology · 2024Article
- Interventions addressing family violence and mental illness or substance use in low- and middle-income countries: A systematic review.Global mental health (Cambridge, England) · 2023Review
- Closing the treatment gap for alcohol use disorders in low- and middle-income countries.Global mental health (Cambridge, England) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
Abstract
HIV-affected families report higher rates of harmful alcohol use, intimate partner violence (IPV) and family conflict, which can have detrimental effects on children. Few evidence-based interventions exist to address these complex issues in Sub-Saharan Africa. This mixed methods study explores the potential of a family-based intervention to reduce IPV, family conflict and problems related to alcohol use to promote child mental health and family functioning within HIV-affected families in post-genocide Rwanda. A family home-visiting, evidence-based intervention designed to identify and enhance resilience and communication in families to promote mental health in children was adapted and developed for use in this context for families affected by caregiver HIV in Rwanda. The intervention was adapted and developed through a series of pilot study phases prior to being tested in open and randomized controlled trials (RCTs) in Rwanda for families affected by caregiver HIV. Quantitative and qualitative data from the RCT are explored here using a mixed methods approach to integrate findings. Reductions in alcohol use and IPV among caregivers are supported by qualitative reports of improved family functioning, lower levels of violence and problem drinking as well as improved child mental health, among the intervention group. This mixed methods analysis supports the potential of family-based interventions to reduce adverse caregiver behaviors as a major mechanism for improving child well-being. Further studies to examine these mechanisms in well-powered trials are needed to extend the evidence-base on the promise of family-based intervention for use in low- and middle-income countries.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.