Evidence map›Paper›PMID 27391933›Full record

ArticleEye (London, England)2016

Spectral-domain optical coherence tomography findings of the macula in 500 consecutive patients with uveitis.

R S Grajewski, A C Boelke, W Adler, S Meyer, A Caramoy, B Kirchhof, C Cursiefen, L M Heindl

Open access · bronzeAbstract read
In one paragraph

Article in Eye (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 44 citations in OpenAlex.

  1. Trial
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  4. Observational
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  9. Mechanisms of macular edema.Frontiers in medicine · 2023
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  17. Dominant cystoid macular dystrophy associated with mutations in theInternational journal of ophthalmology · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

R S GrajewskiDepartment of Ophthalmology, University of Cologne, Cologne, Germany.
A C BoelkeDepartment of Ophthalmology, University of Cologne, Cologne, Germany.
W AdlerDepartment of Biometry and Epidemiology, University Erlangen-Nuremberg, Erlangen, Germany.
S MeyerDepartment of Ophthalmology, University of Cologne, Cologne, Germany.
A CaramoyDepartment of Ophthalmology, University of Cologne, Cologne, Germany.
B KirchhofDepartment of Ophthalmology, University of Cologne, Cologne, Germany.
C CursiefenDepartment of Ophthalmology, University of Cologne, Cologne, Germany.
L M HeindlDepartment of Ophthalmology, University of Cologne, Cologne, Germany.
University of Cologne · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PurposeTo analyze the macular structure in a large series of consecutive patients with different types of uveitis using spectral-domain optical coherence tomography (SD-OCT).Patients and methodsFive hundred eyes of 500 consecutive patients with anterior, intermediate, posterior, and panuveitis underwent standardized macular examination using SD-OCT. Central retinal thickness (CRT), macular volume (MV), and presence of cystoid macular edema (CME), diffuse macular edema (DME), serous retinal detachment (SRD), epiretinal membrane with (ERM+) and without (ERM-) retinal surface wrinkling were determined.ResultsThe anatomic location of inflammation affected significantly CRT and MV (P<0.001, respectively), with the highest values in intermediate and panuveitis. CME was seen in 25% of all uveitic eyes, DME in 11%, SRD in 8%, ERM+ in 18%, and ERM- in 13%. CME was most frequent in intermediate (40%) and panuveitis (36%); DME was most frequent in panuveitis (18%) and posterior uveitis (17%); SRD was most frequent in panuveitis (15%) and posterior uveitis (10%); ERM+ was most frequent in panuveitis (45%) and intermediate uveitis (30%); and ERM- was most frequent in intermediate (14%) and posterior uveitis (15%).ConclusionSD-OCT of the macula is recommended for all uveitis patients. CRT, MV, and the incidence of CME were highest in intermediate and panuveitis.

Indexed as

Tomography, Optical CoherenceAdolescentAdultAgedAged, 80 and overAge of OnsetChildChild, PreschoolEpiretinal MembraneFemaleHumansInfantMacula LuteaMacular EdemaMaleMiddle Aged

Identifiers

PMID27391933
PMCPMC5108004
OpenAlexW2470948656

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.