ArticlePloS one2016
Prevalence of Sexually Transmitted Viral and Bacterial Infections in HIV-Positive and HIV-Negative Men Who Have Sex with Men in Toronto.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 4 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 4 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- Prevalence of gonococcal and chlamydial infections among men who have sex with men in sub-Saharan Africa: a systematic review and meta-analysis.Systematic reviews · 2024Pooled it
- Gonorrhoea: a systematic review of prevalence reporting globally.BMC infectious diseases · 2021Pooled it
- Prevalence and burden of HBV co-infection among people living with HIV: A global systematic review and meta-analysis.Journal of viral hepatitis · 2020Pooled it
- Sexually transmitted hepatitis C virus infections: current trends, and recent advances in understanding the spread in men who have sex with men.Journal of the International AIDS Society · 2019Pooled it
- Pre-vaccination prevalence of anogenital and oral human papillomavirus in young HIV-infected men who have sex with men.Papillomavirus research (Amsterdam, Netherlands) · 2019Trial
- Influencing factors of HCV testing willingness among men who have sex with men in China: A structural equation modeling analysis.PloS one · 2025Article
- Prevalence and Risk Factors of Cytomegalovirus Among Men Having Sex With Men Enrolled in a Pre-Exposure Prophylaxis Study.Open forum infectious diseases · 2024Article
- Prevalence of hepatitis B and C infections among HIV-positive men who have sex with men: A systematic review and meta-analysis.Health science reports · 2024Article
- Herpes Simplex Virus Type 2 Prevalence and Association with Inflammatory Cytokines Among Sexual and Gender Minorities Living With and Without HIV-1 from Lagos, Nigeria.AIDS research and human retroviruses · 2023Article
- Immune markers and microbial factors are related with periodontitis severity in people with HIV.Clinical oral investigations · 2023Article
- Low incidence and prevalence of hepatitis C in two cohorts of HIV pre-exposure prophylaxis adherence interventions in men who have sex with men in Southern California.Journal of viral hepatitis · 2022Article
- National Landscape of Human Immunodeficiency Virus-Positive Deceased Organ Donors in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Article
- Rising syphilis rates in Canada, 2011-2020.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2022Article
- Sociodemographic and Psychological Predictors of Seeking Health Information Online among GB2M in Ontario: Findings from the #iCruise Project.International journal of sexual health : official journal of the World Association for Sexual Health · 2022Article
- Factors associated with HIV/syphilis co-infection initiating of antiretroviral therapy.Revista de saude publica · 2022Article
- LGBTQ+ Aging Research in Canada: A 30-Year Scoping Review of the Literature.Geriatrics (Basel, Switzerland) · 2021Article
- Trends in hepatitis C virus seroprevalence and associated risk factors among men who have sex with men in Montréal: results from three cross-sectional studies (2005, 2009, 2018).Sexually transmitted infections · 2021Article
- HPV genotyping and risk factors for anal high-risk HPV infection in men who have sex with men from Toronto, Canada.Scientific reports · 2021Article
- Article
- STI prevalence among men living with HIV engaged in safer conception care in rural, southwestern Uganda.PloS one · 2021Article
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHepatitis B (HBV), hepatitis C (HCV) and other sexually transmitted infections (STIs) have been associated with HIV transmission risk and disease progression among gay men and other men who have sex with men (MSM), but the frequency and distribution of STIs in this community in Canada has not been extensively studied.
methodsWe recruited MSM living with and without HIV from a large primary care clinic in Toronto. Participants completed a detailed socio-behavioural questionnaire using ACASI and provided blood for syphilis, HIV, HBV and HCV, herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2), and human cytomegalovirus (CMV) serology, urine for chlamydia and gonorrhea, and a self-collected anal swab for human papillomavirus (HPV) molecular diagnostics. Prevalences were expressed as a proportion and compared using chi-square.
results442 MSM were recruited, 294 living with HIV and 148 without. Active syphilis (11.0% vs. 3.4%), ever HBV (49.4% vs. 19.1%), HCV (10.4% vs. 3.4%), HSV-2 (55.9% vs. 38.2%), CMV (98.3% vs. 80.3%) and high-risk (HR) anal HPV (67.6% vs. 51.7%) infections were significantly more common in men living with HIV. Chlamydia and gonorrhea were infrequent in both groups. Regardless of HIV infection status, age and number of lifetime male sexual partners were associated with HBV infection and lifetime injection drug use with HCV infection.
conclusionsSyphilis and viral infections, including HBV, HCV, HSV-2, CMV, and HR-HPV, were common in this clinic-based population of MSM in Toronto and more frequent among MSM living with HIV. This argues for the implementation of routine screening, vaccine-based prevention, and education programs in this high-risk population.
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