ArticleParasites & vectors2016
Multilocus genotypes and broad host-range of Enterocytozoon bieneusi in captive wildlife at zoological gardens in China.
Article in Parasites & vectors, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed.
- First Molecular Detection and Genotypic Characterization of Enterocytozoon bieneusi and Blastocystis in Farmed Chukar Partridges (Alectoris chukar) in Southern China.Acta parasitologica · 2026Article
- Occurrence and Multi-Locus Genotyping ofPathogens (Basel, Switzerland) · 2026Article
- Molecular evidence of host range expansion ofOne health (Amsterdam, Netherlands) · 2025Article
- Genetic diversity of Enterocytozoon bieneusi in 1099 wild animals and 273 imported pastured donkeys in northern China.Parasites & vectors · 2025Article
- Detection and molecular characterization of Blastocystis sp., Enterocytozoon bieneusi and Giardia duodenalis in asymptomatic animals in southeastern Iran.Scientific reports · 2025Article
- Prevalence and molecular characterization ofFrontiers in veterinary science · 2025Article
- Wildlife Pathogens and Zoonotic Disease Risk Assessment in Vietnam: A Wildlife Trade Hotspot.Transboundary and emerging diseases · 2025Review
- Epidemiology and Molecular Characterization of Zoonotic Gastrointestinal Protozoal Infection in Zoo Animals in China.Animals : an open access journal from MDPI · 2024Article
- Occurrence and genotyping of Enterocytozoon bieneusi in flying squirrels (Trogopterus xanthipes) from China.Parasite (Paris, France) · 2024Article
- Molecular Characterization ofAnimals : an open access journal from MDPI · 2023Article
- Occurrence and Molecular Characteristics of Microsporidia in Captive Red Pandas (Animals : an open access journal from MDPI · 2023Article
- First description ofFrontiers in cellular and infection microbiology · 2023Article
- Molecular detection and characterization of Enterocytozoon bieneusi in captive alpine musk deer (Moschus chrysogaster) in Central and Eastern of Gansu Province, China.Veterinary research communications · 2022Article
- Prevalence and new genotypes ofInternational journal for parasitology. Parasites and wildlife · 2022Article
- Molecular Epidemiology and Genetic Diversity ofAnimals : an open access journal from MDPI · 2022Article
- Prevalence and genetic diversity ofInternational journal for parasitology. Parasites and wildlife · 2022Article
- High zoonotic potential of Cryptosporidium spp., Giardia duodenalis, and Enterocytozoon bieneusi in wild nonhuman primates from Yunnan Province, China.Parasites & vectors · 2022Article
- First genotyping of Enterocytozoon bieneusi in plateau pikas (Ochotona curzoniae) from the Qinghai Plateau, Northwest China.Veterinary research communications · 2021Article
- Prevalence and Novel Genotypes Identification ofAnimals : an open access journal from MDPI · 2021Article
- Ecological and public health significance ofOne health (Amsterdam, Netherlands) · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEnterocytozoon bieneusi is a common opportunistic pathogen that is widely detected in humans, domestic animals and wildlife, and poses a challenge to public health. The present study was performed to evaluate the prevalence, genotypic diversity and zoonotic potential of E. bieneusi among wildlife at Chengdu and Bifengxia zoological gardens in Sichuan Province, China.
resultsOf the 272 fresh fecal samples harvested from 70 captive wildlife species at Chengdu Zoo (n = 198) and Bifengxia Zoo (n = 74), 21 (10.6 %) and 22 (29.7 %) tested positive for E. bieneusi by internal transcribed spacer (ITS) sequencing analysis, respectively. Specifically, genotypes D, Peru 6, CHB1, BEB6, CHS9, SC02 and SC03, and genotypes D, CHB1, SC01 and SC02 were detected in the Chengdu and Bifengxia Zoo samples, respectively. Five known genotypes (D, Peru 6, BEB6, CHS9 and CHB1) and three novel genotypes (SC01, SC02 and SC03) were clustered into the zoonotic group (group 1) and host-adapted group (group 2). Multilocus sequence typing (MLST) analysis targeting three microsatellites (MS1, MS3 and MS7) and one minisatellite (MS4) were successfully sequenced for 37, 33, 35 and 37 specimens, generating 8, 3, 11 and 15 distinct locus types, respectively. Altogether, we identified 27 multilocus genotypes (MLGs) among the E. bieneusi isolates by MLST. These data highlight the high genetic diversity of E. bieneusi among zoo wildlife.
conclusionsTo our knowledge, this is the first report on the prevalence and genotypic diversity of E. bieneusi infections among captive wildlife in zoos in southwest China. Notably, we identified three novel E. bieneusi genotypes, as well as six new mammalian hosts (Asian golden cats, Tibetian blue bears, blackbucks, hog deer, Malayan sun bears and brown bears) for this organism. Moreover, the occurrence of zoonotic genotypes suggests that wildlife may act as reservoirs of E. bieneusi that can serve as a source of human microsporidiosis. The findings presented here should contribute to the control of zoonotic disease in China.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.