Evidence map›Paper›PMID 27391218›Full record

ReviewOrganogenesis2016

A concise review of common animal models for the study of limb regeneration.

Zayd Farah, Huimin Fan, Zhongmin Liu, Jia-Qiang He

Abstract readReview
In one paragraph

Review in Organogenesis, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zayd Faraha Department of Biomedical Sciences & Pathobiology , Center for Veterinary Regenerative Medicine (CVRM), Virginia-Maryland College of Veterinary Medicine, Virginia Tech , Blacksburg , VA , USA.
Huimin Fanb Research Institute of Heart Failure , Shanghai East Hospital of Tongji University , Shanghai , China.
Zhongmin Liub Research Institute of Heart Failure , Shanghai East Hospital of Tongji University , Shanghai , China.
Jia-Qiang Hea Department of Biomedical Sciences & Pathobiology , Center for Veterinary Regenerative Medicine (CVRM), Virginia-Maryland College of Veterinary Medicine, Virginia Tech , Blacksburg , VA , USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Correct selection of an appropriate animal mode to closely mimic human extremity diseases or to exhibit desirable phenotypes of limb regeneration is the first critical step for all scientists in biomedical and regenerative researches. The commonly-used animals in limb regeneration and repairing studies, such as axolotl, mice, and rats, are discussed in the review and other models including cockroaches, dogs, and horses are also mentioned. The review weighs the general advantages, disadvantages, and precedent uses of each model in the context of limb and peripheral injury and subsequent regeneration. We hope that this review can provide the reader an overview of each model, from which to select one for their specific purpose.

Indexed as

AnimalsCaudataExtremitiesMammalsModels, AnimalRegenerationamputationaxolotlcockroachdoghorselimb diseasesmouserat

Identifiers

PMID27391218
PMCPMC4993303

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.