Evidence map›Paper›PMID 27390777›Full record

ArticleNeurotransmitter (Houston, Tex.)

Inhibition of mammillary body neurons by direct activation of Group II metabotropic glutamate receptors.

Charles C Lee

Open access · diamondAbstract read
In one paragraph

Article in Neurotransmitter (Houston, Tex.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Charles C LeeDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803.
Louisiana State University · US

Funding

Functional architecture of the auditory cortexR03DC011361 · NIDCD · UNIVERSITY OF CHICAGO · PI LEE, CHARLES C · 2011 to 2013
$439k
Alterations to corticothalamic circuitry in a mouse model of autismR03MH104851 · NIMH · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI LEE, CHARLES C · 2015 to 2016
$196k
NIDCD NIH HHS R03 DC011361NIMH NIH HHS R03 MH104851
6 · The paper itself

Abstract

The mammillary body is an important neural component of limbic circuitry implicated in learning and memory. Excitatory and inhibitory inputs, primarily mediated by glutamate and gamma-amino butyric acid (GABA), respectively, converge and integrate in this region, before sending information to the thalamus. One potentially overlooked mechanism for inhibition of mammillary body neurons is through direct activation of Group II metabotropic glutamate receptors (mGluRs). Here, whole-cell patch clamp recordings of

Indexed as

glutamateGroup II mGluRinhibitionlimbic systemmammillary bodymetabotropic glutamate receptor

Identifiers

PMID27390777
PMCPMC4933320
OpenAlexW2486442130

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.