ArticleEnvironmental epigenetics
Developmental origins of epigenetic transgenerational inheritance.
Article in Environmental epigenetics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
61 citing papers in PubMed.
- Early Nutritional Programing: Unlocking the Potential of Fish for Sustainable Aquaculture.Aquaculture nutrition · 2026Review
- The Evolutionary Misfit: Evolution, Epigenetics, and the Rise of Non-Communicable Diseases.Epigenomes · 2025Review
- Paternal transgenerational epigenetic effects: high fat diet induced obesity alters miRNA expression in F1 and F2 C57BL/6 male mice.Molecular genetics and genomics : MGG · 2025Article
- Diabetes and male infertility: A review of sperm chromatin damage and epigenetic effects.International journal of reproductive biomedicine · 2025Review
- Recurrent spontaneous miscarriages from sperm after ABVD chemotherapy in a patient with Hodgkin's lymphoma: sperm DNA and methylation profiling.Asian journal of andrology · 2025Article
- Review
- An interdisciplinary fetal neonatal neurology collaborative promotes integrative life-course brain health.Frontiers in neurology · 2025Review
- History of exposure to copper influences transgenerational gene expression responses inEpigenetics · 2024Article
- Review
- Epigenetics Research in Evolutionary Biology: Perspectives on Timescales and Mechanisms.Molecular biology and evolution · 2024Review
- Parental developmental experience affects vocal learning in offspring.Scientific reports · 2024Article
- The Molecular Basis of the Augmented Cardiovascular Risk in Offspring of Mothers with Hypertensive Disorders of Pregnancy.International journal of molecular sciences · 2024Review
- Genome-wide comparative methylation analysis reveals the fate of germ stem cells after surrogate production in teleost.BMC biology · 2024Article
- Environmental conditions elicit a slow but enduring response of histone post-translational modifications in Mozambique tilapia.Environmental epigenetics · 2024Article
- Epigenetic influences of mobile genetic elements on ciliate genome architecture and evolution.The Journal of eukaryotic microbiology · 2022Review
- Multigenerational Exposure to Uranium Changes Sperm Metabolome in Rats.International journal of molecular sciences · 2022Article
- Impact of Neonatal Activation of Nuclear Receptor CAR (Nr1i3) on Cyp2 Gene Expression in Adult Mouse Liver.Toxicological sciences : an official journal of the Society of Toxicology · 2022Article
- Pollution induces epigenetic effects that are stably transmitted across multiple generations.Evolution letters · 2022Article
- The Exposome and Toxicology: A Win-Win Collaboration.Toxicological sciences : an official journal of the Society of Toxicology · 2022Review
- Role of epigenetic transgenerational inheritance in generational toxicology.Environmental epigenetics · 2022Review
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Environmental factors can induce epigenetic alterations in the germ cells that can potentially be transmitted transgenerationally. This non-genetic form of inheritance is termed epigenetic transgenerational inheritance and has been shown in a variety of species including plants, flies, worms, fish, rodents, pigs, and humans. This phenomenon operates during specific critical windows of exposure, linked to the developmental biology of the germ cells (sperm and eggs). Therefore, concepts of the developmental origins of transgenerational inheritance of phenotypic variation and subsequent disease risk need to include epigenetic processes affecting the developmental biology of the germ cell. These developmental impacts on epigenetic transgenerational inheritance, in contrast to multigenerational exposures, are the focus of this Perspective.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.