Evidence map›Paper›PMID 27390559›Full record

ArticleHand (New York, N.Y.)2016

Wide Awake Trigger Finger Release Surgery: Prospective Comparison of Lidocaine, Marcaine, and Exparel.

Constantinos Ketonis, Nayoung Kim, Frederic Liss, Benjamin Zmistowski, Jonas Matzon, Charles Leinberry, Mark Wang, Christopher Jones, Jack Abboudi, William Kirkpatrick and 1 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Hand (New York, N.Y.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03867539 (Exparel and Education to Avoid Opioids After Carpal Tunnel Release), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03867539 phase4recruitingnot on this mapstarted 2019, after this paper: background citation

Exparel and Education to Avoid Opioids After Carpal Tunnel Release

TypeinterventionalSponsorKettering Health NetworkRan2019 to 2027Enrolled64ConditionsCarpal Tunnel SyndromeArmsDiffering pain management strategy
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Constantinos KetonisThomas Jefferson University Hospital, Philadelphia, PA, USA.
Nayoung KimThomas Jefferson University Hospital, Philadelphia, PA, USA.
Frederic LissThomas Jefferson University Hospital, Philadelphia, PA, USA.
Benjamin ZmistowskiThomas Jefferson University Hospital, Philadelphia, PA, USA.
Jonas MatzonThomas Jefferson University Hospital, Philadelphia, PA, USA.
Charles LeinberryThomas Jefferson University Hospital, Philadelphia, PA, USA.
Mark WangThomas Jefferson University Hospital, Philadelphia, PA, USA.
Christopher JonesThomas Jefferson University Hospital, Philadelphia, PA, USA.
Jack AbboudiThomas Jefferson University Hospital, Philadelphia, PA, USA.
William KirkpatrickThomas Jefferson University Hospital, Philadelphia, PA, USA.
Asif M IlyasThomas Jefferson University Hospital, Philadelphia, PA, USA.
Thomas Jefferson University Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLocal anesthetics are routinely used in hand surgery for procedures such as trigger finger releases (TFRs). However, little is known as to the difference in efficacy and patient experience with various local anesthetics. We prospectively evaluated the efficacy of Lidocaine (L), Marcaine (M), and Exparel (E) to elucidate differences in pain scores and opioid consumption between these groups.

methodsAll consecutive TFR performed over a 6-month period in 2014 at our institution were divided to receive Lidocaine, Marcaine, or Marcaine with postoperative Exparel. Pain levels, daily opioid consumption, and adverse reactions were recorded and analyzed for postoperative day (POD) 0-3.

resultsA total of 154 patients were enrolled (L:53, M:50, E:51). The Lidocaine group reported the highest pain levels for POD 0-1. Marcaine pain levels were similar to Exparel on POD 0 but higher on POD 1. Opioid consumption on POD 0-1 was significantly different with E:27%, M:58% and L:59% as was the number of pills consumed (E:0.70, M: 1.08 and L:1.62). In addition, 50% of Exparel patients required no pain medications and experienced significantly less adverse reactions (E:4%, M:10%, L:13%). By POD 2-3, there were no statistical differences between the 3 groups.

conclusionsPatients treated with Marcaine attain better pain control than Lidocaine on POD 0-1but only patients who received Exparel maintained the lowest pain levels through POD 0-3 while using little-to-no opioid medications and with less adverse reactions than Lidocaine or Marcaine alone.

Indexed as

ExparelLidocaineMarcainetrigger fingerwide awake

Identifiers

PMID27390559
PMCPMC4920533
OpenAlexW2297428970

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.