ArticleKorean journal of radiology
Diffusion-Weighted MRI of Malignant versus Benign Portal Vein Thrombosis.
Article in Korean journal of radiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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15 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Contrast-enhanced ultrasound for the characterization of portal vein thrombosis vs tumor-in-vein in HCC patients: a systematic review and meta-analysis.European radiology · 2020Pooled it
- The Thoracic Footprint of Hepatocellular Carcinoma: A Mechanism-Based Imaging Narrative Review.Diagnostics (Basel, Switzerland) · 2026Review
- Imaging and management of biliary complications after biliary interventions.Abdominal radiology (New York) · 2026Review
- Portal vein tumor thrombosis in hepatocellular carcinoma patients: Is it the end?Liver research (Beijing, China) · 2024Review
- Value of susceptibility-weighted imaging in differentiating benign from malignant portal vein thrombosis.Quantitative imaging in medicine and surgery · 2023Article
- Portal vein thrombosis on unenhanced MRI: a case series.BJR case reports · 2023Article
- Current Landscape and Future Perspectives of Abbreviated MRI for Hepatocellular Carcinoma Surveillance.Korean journal of radiology · 2022Review
- MRI diffusion-weighted imaging detects a fresh portal vein thrombus as a high intensity lesion in a patient with a liver transplant: A case report.Acta radiologica open · 2021Article
- The Progress in the Treatment of Hepatocellular Carcinoma With Portal Vein Tumor Thrombus.Frontiers in oncology · 2021Review
- Hepatocellular carcinoma with macrovascular invasion: multimodality imaging features for the diagnosis.Diagnostic and interventional radiology (Ankara, Turkey) · 2020Article
- Tumor in the veins: an abdominal perspective with an emphasis on CT and MR imaging.Insights into imaging · 2020Review
- Tumor thrombus: incidence, imaging, prognosis and treatment.Cardiovascular diagnosis and therapy · 2017Review
- Selection and Reporting of Statistical Methods to Assess Reliability of a Diagnostic Test: Conformity to Recommended Methods in a Peer-Reviewed Journal.Korean journal of radiologyArticle
- The Diagnostic Performance of Liver MRI without Intravenous Contrast for Detecting Hepatocellular Carcinoma: A Case-Controlled Feasibility Study.Korean journal of radiologyArticle
- Diffusion-Weighted MRI for the Initial Viability Evaluation of Parasites in Hepatic Alveolar Echinococcosis: Comparison with Positron Emission Tomography.Korean journal of radiologyArticle
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6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo validate the diffusion-weighted MRI (DWI) for differentiation of benign from malignant portal vein thrombosis. MATERIALS AND
methodsThe Institutional Review Board approved this retrospective study and waived informed consent. A total of 59 consecutive patients (52 men and 7 women, aged 40-85 years) with grossly defined portal vein thrombus (PVT) on hepatic MRI were retrospectively analyzed. Among them, liver cirrhosis was found in 45 patients, and hepatocellular carcinoma in 47 patients. DWI was performed using b values of 50 and 800 sec/mm(2) at 1.5-T unit. A thrombus was considered malignant if it enhanced on dynamic CT or MRI; otherwise, it was considered bland. There were 18 bland thrombi and 49 malignant thrombi in 59 patients, including 8 patients with simultaneous benign and malignant PVT. Mean apparent diffusion coefficients (ADCs) of benign and malignant PVTs were compared by using Mann-Whitney U test. Diagnostic accuracy was evaluated using receiver operating characteristic (ROC) curve analysis.
resultsThe mean ADC ± standard deviation of bland and malignant PVT were 1.00 ± 0.39 × 10(-3) mm(2)/sec and 0.92 ± 0.25 × 10(-3) mm(2)/sec, respectively; without significant difference (p = 0.799). The area under ROC curve for ADC was 0.520. An ADC value of > 1.35 × 10(-3) mm(2)/sec predicted bland PVT with a specificity of 94.6% (95% confidence interval [CI]: 84.9-98.9%) and a sensitivity of 22.2% (95% CI: 6.4-47.6%), respectively.
conclusionDue to the wide range and considerable overlap of the ADCs, DWI cannot differentiate the benign from malignant thrombi efficiently.
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