Evidence map›Paper›PMID 27390314›Full record

ArticleAJNR. American journal of neuroradiology2016

Geographic Differences in Endovascular Treatment and Retreatment of Cerebral Aneurysms.

A S Turk, S C Johnston, S Hetts, J Mocco, J English, Y Murayama, C J Prestigiacomo, D Lopes, Y P Gobin, K Carroll and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AJNR. American journal of neuroradiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Long term WEB results - still going strong at 5 years?Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024
    Article
  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

A S TurkFrom the Departments of Radiology (A.S.T.) turk@musc.edu.ORCID http://orcid.org/0000-0001-8375-0410
S C JohnstonClinical and Translational Science Institute (S.C.J.), University of California, San Francisco, San Francisco, California.ORCID http://orcid.org/0000-0002-2912-0714
S HettsDepartment of Radiology and Biomedical Imaging (S.H.), University of California, San Francisco School of Medicine, San Francisco, California.ORCID http://orcid.org/0000-0001-5885-7259
J MoccoDepartment of Neurosurgery (J.M.), Icahn School of Medicine at Mount Sinai, New York, New York.ORCID http://orcid.org/0000-0001-5489-2524
J EnglishCalifornia Pacific Medical Center (J.E.), San Francisco, California.ORCID http://orcid.org/0000-0001-8943-6000
Y MurayamaDepartment of Neurosurgery (Y.M.), Jikei University Hospital, Tokyo, Japan.ORCID http://orcid.org/0000-0003-3490-385X
C J PrestigiacomoDepartment of Neurological Surgery (C.J.P.), University of Medicine and Dentistry of New Jersey, Newark, New Jersey.ORCID http://orcid.org/0000-0002-5979-2378
D LopesDepartment of Neurosurgery (D.L.), Rush University Medical Center, Chicago, Illinois.ORCID http://orcid.org/0000-0002-6280-0113
Y P GobinDepartment of Neurosurgery (Y.P.G.), Weill Cornell Medical College, New York, New York.ORCID http://orcid.org/0000-0002-3774-9096
K CarrollStryker Corporation (K.C.), Fremont, California.ORCID http://orcid.org/0000-0002-9861-0274
C McDougallDepartment of Neurosurgery (C.M.), Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona.ORCID http://orcid.org/0000-0001-7372-7049

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeComparing outcomes between endovascular aneurysm coiling trials can be difficult because of heterogeneity in patients and end points. We sought to understand the impact of geography on aneurysm retreatment in patients enrolled in the Matrix and Platinum Science Trial. MATERIALS AND

methodsPost hoc analysis was performed on data from the Matrix and Platinum Science trial. Patients were stratified as either North American or international. Baseline patient demographics, comorbidities, aneurysm characteristics, procedural complications, and clinical and angiographic outcomes were compared.

resultsWe evaluated 407 patients from 28 North American sites and 219 patients from 15 international sites. Patient demographics differed significantly between North American and international sites. Aneurysms were well occluded postprocedure more often at international than North American sites (

conclusionsData from the Matrix and Platinum Science Trial demonstrate that aneurysm retreatment occurs with different frequency and at different times in different regions of the world. This trend has critical value when interpreting trials reporting short-term outcomes, especially when judgment-based metrics such as retreatment are primary end points that may or may not take place within the defined study follow-up period. Though these variations can be controlled for and balanced within a given randomized trial, such differences in practice patterns must be accounted for in any attempt to compare outcomes between different trials. Despite these differences, endovascular-treated intracranial aneurysms around the world have similar clinical outcomes.

Identifiers

PMID27390314
PMCPMC7963770

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.