ArticleCerebral cortex (New York, N.Y. : 1991)2017
Correlations Between Personality and Brain Structure: A Crucial Role of Gender.
Article in Cerebral cortex (New York, N.Y. : 1991), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 3 syntheses or guidelines pooled it, 95 citations in OpenAlex.
- Extraversion and the resting brain: a coordinate-based meta-analysis of resting-state functional brain imaging studies.Brain structure & function · 2025Pooled it
- Gray matter structures associated with neuroticism: A meta-analysis of whole-brain voxel-based morphometry studies.Human brain mapping · 2021Pooled it
- Brain gray matter correlates of extraversion: A systematic review and meta-analysis of voxel-based morphometry studies.Human brain mapping · 2019Pooled it
- Aberrant multivariate mapping between behavioral profiles and cortical morphological brain networks in children with autism spectrum disorder.Translational psychiatry · 2026Article
- Profiles Vulnerable to Maladaptive Use of Recreational Digital Environments Identified Using the Big Five Model.Behavioral sciences (Basel, Switzerland) · 2025Article
- The Relationship Between Intelligence and Personality Traits Differentiated by Gender in Spanish Adolescents.Children (Basel, Switzerland) · 2025Article
- Network-based mapping and neurotransmitter architecture of brain gray matter correlates of extraversion.Frontiers in systems neuroscience · 2025Article
- Network-based mapping and neurotransmitter architecture of gray matter correlates of neuroticism.Frontiers in systems neuroscience · 2025Article
- From big associations to big practices-Why normative modeling should be the default in personality neuroscience.Frontiers in psychology · 2025Article
- Weak and unstable prediction of personality from the structural connectome.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Brain identification of IBS patients based on GBDT and multiple imaging techniques.Physical and engineering sciences in medicine · 2024Article
- Insights into Sex and Gender Differences in Brain and Psychopathologies Using Big Data.Life (Basel, Switzerland) · 2023Review
- Impact of sex and serum lipids interaction on working memory: A large-scale brain networks study.Brain and behavior · 2023Article
- Sex-dependent gut microbiota-brain-cognition associations: a multimodal MRI study.BMC neurology · 2023Article
- Stability of associations between neuroticism and microstructural asymmetry of the cingulum during late childhood and adolescence: Insights from a longitudinal study with up to 11 waves.Human brain mapping · 2023Article
- Article
- Does the Personality of Consumers Influence the Assessment of the Experience of Interaction with Social Robots?International journal of social robotics · 2022Article
- Brain network topology and personality traits: A source level magnetoencephalographic study.Scandinavian journal of psychology · 2022Article
- Choice of Voxel-based Morphometry processing pipeline drives variability in the location of neuroanatomical brain markers.Communications biology · 2022Article
- Sex Differences in Acute Neuroendocrine Responses to Stressors in Rodents and Humans.Cold Spring Harbor perspectives in biology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Previous studies have shown that males and females differ in personality and gender differences have also been reported in brain structure. However, effects of gender on this "personality-brain" relationship are yet unknown. We therefore investigated if the neural correlates of personality differ between males and females. Whole brain voxel-based morphometry was used to investigate the influence of gender on associations between NEO FFI personality traits and gray matter volume (GMV) in a matched sample of 182 males and 182 females. In order to assess associations independent of and dependent on gender, personality-GMV relationships were tested across the entire sample and separately for males and females. There were no significant correlations between any personality scale and GMV in the analyses across the entire sample. In contrast, significant associations with GMV were detected for neuroticism, extraversion, and conscientiousness only in males. Interestingly, GMV in left precuneus/parieto-occipital sulcus correlated with all 3 traits. Thus, our results indicate that brain structure-personality relationships are highly dependent on gender, which might be attributable to hormonal interplays or differences in brain organization between males and females. Our results thus provide possible neural substrates of personality-behavior relationships and underline the important role of gender in these associations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.