Evidence map›Paper›PMID 27389777›Full record

ArticleMolecular neurobiology2017

Noggin Along with a Self-Assembling Peptide Nanofiber Containing Long Motif of Laminin Induces Tyrosine Hydroxylase Gene Expression.

Shima Tavakol, Sayed Mostafa Modaress Musavi, Behnaz Tavakol, Elham Hoveizi, Jafar Ai, Seyed Mahdi Rezayat

Erratum issuedAbstract read
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In one paragraph

Article in Molecular neurobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 1 country.

Shima TavakolDrug Nanocarriers Research Core, Razi Drug Research Center, Iran University of Medical Sciences, Tehran, Iran. tavakol.sh@iums.ac.ir.
Sayed Mostafa Modaress MusaviShefa Neuroscience Research Center, Khatam al-Anbia Hospital, Tehran, Iran.
Behnaz TavakolSchool of Medicine, Kashan University of Medical Sciences, Isfahan, Iran.
Elham HoveiziDepartment of Biology, Faculty of Sciences, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
Jafar AiDepartment of Tissue Engineering, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Seyed Mahdi RezayatDepartment of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Iran University of Medical Sciences · IRIslamic Azad University Pharmaceutical Sciences Branch · IRKashan University of Medical Sciences · IRKhatam University · IRShahid Chamran University of Ahvaz · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tyrosine hydroxylase (TH), a rate-limiting step in catecholamine synthesis in which its activity influences Alzheimer disease, Parkinson disease, and IQ of schizophrenia patients, has been studied for a long time. In the meantime, the present investigation assessed the effect of noggin and type of self-assembling nanofibers in TH gene over-expression by neuron-like cells derived from human endometrial-derived stromal cells (hEnSCs). Neuroblastoma cells and hEnSCs encapsulated into nanofibers including Matrigel, (RADA)

Indexed as

Carrier ProteinsCell Line, TumorCell ShapeCell SurvivalEndometriumFemalegamma-Aminobutyric AcidGene Expression Regulation, EnzymologicGlial Fibrillary Acidic ProteinHumansLamininNanofibersNoggin ProteinPeptidesProto-Oncogene Proteins c-bcl-2Real-Time Polymerase Chain ReactionCarrier Proteinsgamma-Aminobutyric AcidGlial Fibrillary Acidic ProteinLamininNoggin ProteinPeptidesProto-Oncogene Proteins c-bcl-2TubulinTyrosine 3-MonooxygenaseBMHP-1Laminin motifNogginSelf-assembling peptide nanofiberTyrosine hydroxylase

Identifiers

PMID27389777
OpenAlexW2466076814

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.