Evidence map›Paper›PMID 27389578›Full record

ArticleActa neurologica Belgica2016

Detection superiority of 7 T MRI protocol in patients with epilepsy and suspected focal cortical dysplasia.

A J Colon, M J P van Osch, M Buijs, J V D Grond, P Boon, M A van Buchem, P A M Hofman

Abstract read
In one paragraph

Article in Acta neurologica Belgica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  10. UltraHigh Field MR Imaging in Epilepsy.Magnetic resonance imaging clinics of North America · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

A J ColonAcademic Center for Epileptology Kempenhaeghe, Maastricht Universitair Medisch Centrum + (MUMC+), Sterkselseweg 65, 5590 VE, Heeze, The Netherlands. colona@kempenhaeghe.nl.
M J P van OschDepartment of Radiology, Leiden University Medical Centre, Leiden, The Netherlands.
M BuijsDepartment of Radiology, Leiden University Medical Centre, Leiden, The Netherlands.
J V D GrondDepartment of Radiology, Leiden University Medical Centre, Leiden, The Netherlands.
P BoonAcademic Center for Epileptology Kempenhaeghe, Maastricht Universitair Medisch Centrum + (MUMC+), Sterkselseweg 65, 5590 VE, Heeze, The Netherlands.
M A van BuchemDepartment of Radiology, Leiden University Medical Centre, Leiden, The Netherlands.
P A M HofmanAcademic Center for Epileptology Kempenhaeghe, Maastricht Universitair Medisch Centrum + (MUMC+), Sterkselseweg 65, 5590 VE, Heeze, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 11 adult patients with suspicion of Focal cortical dysplasia (FCD) on 1.5 T (n = 1) or 3 T (n = 10) magnetic resonance imaging (MRI), 7 T MRI was performed. Visibility, extent, morphological features and delineation were independently rated and subsequently discussed by three observers. Additionally, head-to-head comparisons with corresponding 3 T images were made in the eight patients with a previous 3 T MRI and sustained suspicion of FCD. Comparison with histopathology was done in the five patients that underwent surgery. All lesions, seen at 1.5 and 3 T, were also recognized on 7 T. At 7 T FLAIR highlighted the FCD-like lesions best, whereas T2 and T2* were deemed better suited to review structure and extent of the lesion. Image quality with the used 7 T MRI setup was higher than the quality with the used 3 T MRI setup. In 2 out of 11 patients diagnosis changed, in one after re-evaluation of the images, and in the other based on histopathology. With the used 7 T MRI setup, FCD-like lesions can be detected with more confidence and detail as compared to lower field strength. However, concordance between radiologic diagnosis and final diagnosis seems to be lower than expected.

Indexed as

Magnetic Resonance ImagingAdultBrainDiagnosis, DifferentialDiagnostic ErrorsEpilepsyFemaleHumansMaleMalformations of Cortical DevelopmentMiddle AgedYoung Adult7 T MRIEpilepsyFocal cortical dysplasiaHumanMisdiagnosis

Identifiers

PMID27389578
PMCPMC4989014

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.