Evidence map›Paper›PMID 27389256›Full record

ArticleJournal of the International AIDS Society2016

Impact of a youth-friendly HIV clinic: 10 years of adolescent outcomes in Port-au-Prince, Haiti.

Lindsey K Reif, Rachel Bertrand, Charles Benedict, Matthew R Lamb, Vanessa Rouzier, Rose Verdier, Warren D Johnson, Jean W Pape, Daniel W Fitzgerald, Louise Kuhn and 1 more

Abstract read
In one paragraph

Article in Journal of the International AIDS Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  18. "FANMI": A Promising Differentiated Model of HIV Care for Adolescents in Haiti.Journal of acquired immune deficiency syndromes (1999) · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lindsey K ReifCenter for Global Health, Weill Cornell Medical College, New York, NY, USA.
Rachel BertrandGroupe Haitien d'Etude du Sarcome de Kaposi et des Infections Opportunistes (GHESKIO), Port-au-Prince, Haiti.
Charles BenedictGroupe Haitien d'Etude du Sarcome de Kaposi et des Infections Opportunistes (GHESKIO), Port-au-Prince, Haiti.
Matthew R LambDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.
Vanessa RouzierGroupe Haitien d'Etude du Sarcome de Kaposi et des Infections Opportunistes (GHESKIO), Port-au-Prince, Haiti.
Rose VerdierGroupe Haitien d'Etude du Sarcome de Kaposi et des Infections Opportunistes (GHESKIO), Port-au-Prince, Haiti.
Warren D JohnsonCenter for Global Health, Weill Cornell Medical College, New York, NY, USA.
Jean W PapeCenter for Global Health, Weill Cornell Medical College, New York, NY, USA.
Daniel W FitzgeraldCenter for Global Health, Weill Cornell Medical College, New York, NY, USA.
Louise KuhnGertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Margaret L McNairyCenter for Global Health, Weill Cornell Medical College, New York, NY, USA.

Funding

Global Health Research Training in HIV and TuberculosisK24AI098627 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI FITZGERALD, DANIEL W · 2012 to 2022
$1.8M
Research training to improve ART adherence among HIV-infected adolescents in HaitiD43TW009606 · FIC · WEILL MEDICAL COLL OF CORNELL UNIV · PI FITZGERALD, DANIEL W · 2013 to 2017
$1.6M
Natural History and Pathogenesis of HPV/HIV co-infection in HaitiR01CA142422 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI FITZGERALD, DANIEL W · 2010 to 2012
$1.0M
FIC NIH HHS D43 TW009606NCI NIH HHS R01 CA142422NIAID NIH HHS K24 AI098627
6 · The paper itself

Abstract

introductionAdolescents account for over 40% of new HIV infections in Haiti. This analysis compares outcomes among HIV-positive adolescents before and after implementation of an adolescent HIV clinic in Port-au-Prince, Haiti.

methodsWe conducted a cohort study using programmatic data among HIV-positive adolescents aged 13 to 19. Data from 41,218 adolescents who were HIV tested from January 2003 to December 2012 were included. Outcomes across the HIV care cascade were assessed before and after implementation of an adolescent clinic (2009), including HIV testing, enrolment in care, assessment for antiretroviral therapy (ART) eligibility, ART initiation and 12-month retention. Pre-ART outcomes were assessed 12 months after HIV testing. Factors associated with pre-ART and ART attrition were identified through multivariable competing risk and Cox proportional hazards regression modelling.

resultsCumulatively, 1672 (4.1%) adolescents tested HIV positive (80% female, median age 16 years). Retention by cascade step comparing pre- and post-clinic included the following: 86% versus 87% of patients enrolled in care, 61% versus 79% were assessed for ART eligibility, 85% versus 92% initiated ART and 68% versus 66% were retained 12 months after ART initiation. Pre-ART attrition decreased from 61% pre-clinic to 50% post-clinic (p<0.001). Pre-ART attrition was associated with being female (sub-distributional hazard ratio (sHR): 1.59; CI: 1.31-1.93), syphilis diagnosis (sHR: 1.47; CI: 1.16-1.85) and slum residence (sHR: 0.84; CI: 0.72-0.97). ART attrition was associated with syphilis diagnosis (hazard ratio (HR): 2.23; CI: 1.35-3.68) and CD4 <50 cells/µL (HR: 1.88; CI: 1.15-3.06).

conclusionsImplementation of a youth-friendly adolescent clinic improved retention in HIV care among adolescents, particularly in the assessment of ART eligibility and ART initiation. Additional interventions are needed to improve retention among pre-ART patients and support long-term retention among ART patients.

Indexed as

Ambulatory Care FacilitiesAdolescentAnti-HIV AgentsCD4 Lymphocyte CountCohort StudiesEligibility DeterminationFemaleHaitiHIV InfectionsHumansMaleProportional Hazards ModelsSyphilisYoung AdultAnti-HIV AgentsadolescentattritionepidemiologyHIV/AIDSretentionyouth

Identifiers

PMID27389256
PMCPMC4933795

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.