ArticlePediatric cardiology2016
Changes in Central Aortic Pressure Levels, Wave Components and Determinants Associated with High Peripheral Blood Pressure States in Childhood: Analysis of Hypertensive Phenotype.
Article in Pediatric cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 35 citations in OpenAlex.
- Central-to-peripheral blood pressure amplification: role of the recording site, technology, analysis approach, and calibration scheme in invasive and non-invasive data agreement.Frontiers in cardiovascular medicine · 2023Article
- Direct estimation of central aortic pressure from measured or quantified mean and diastolic brachial blood pressure: agreement with invasive records.Frontiers in cardiovascular medicine · 2023Article
- Non-invasive central aortic pressure measurement: what limits its application in clinical practice?Frontiers in cardiovascular medicine · 2023Article
- Aortic systolic and pulse pressure invasively and non-invasively obtained: Comparative analysis of recording techniques, arterial sites of measurement, waveform analysis algorithms and calibration methods.Frontiers in physiology · 2023Article
- Effects of L-Citrulline Supplementation and Aerobic Training on Vascular Function in Individuals with Obesity across the Lifespan.Nutrients · 2021Review
- Changes in Body Size during Early Growth Are Independently Associated with Arterial Properties in Early Childhood.Journal of cardiovascular development and disease · 2021Article
- Cardiovascular risk assessment in children and adolescents with congenital solitary kidneys.Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
- Obese and Type 2 Diabetic Youth Have Increased Forward and Backward Wave Reflections.Arteriosclerosis, thrombosis, and vascular biology · 2021Article
- Predictors and reference equations for augmentation index, an arterial stiffness marker, in healthy children and adolescents.Clinics (Sao Paulo, Brazil) · 2021Observational
- Body Composition and Physical Fitness Affect Central Hemodynamics in Young Children.Frontiers in pediatrics · 2021Article
- Haemodynamics of Hypertension in Children.Current hypertension reports · 2020Review
- Arterial Structural and Functional Characteristics at End of Early Childhood and Beginning of Adulthood: Impact of Body Size Gain during Early, Intermediate, Late and Global Growth.Journal of cardiovascular development and disease · 2019Article
- Central systolic blood pressure and central pulse pressure predict left ventricular hypertrophy in hypertensive children.Pediatric nephrology (Berlin, Germany) · 2019Article
- Applications of arterial stiffness markers in peripheral arterial disease.Jornal vascular brasileiro · 2019Review
- Article
- Peripheral and Central Aortic Pressure, Wave-Derived Reflection Parameters, Local and Regional Arterial Stiffness and Structural Parameters in Children and Adolescents: Impact of Body Mass Index Variations.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2018Article
- Reference Intervals of Central Aortic Blood Pressure and Augmentation Index Assessed with an Oscillometric Device in Healthy Children, Adolescents, and Young Adults from Argentina.International journal of hypertension · 2018Article
- High Blood Pressure States in Children, Adolescents, and Young Adults Associate Accelerated Vascular Aging, with a Higher Impact in Females' Arterial Properties.Pediatric cardiology · 2017Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aims were to determine whether children's high peripheral blood pressure states (HBP) are associated with increased central aortic blood pressure (BP) and to characterize hemodynamic and vascular changes associated with HBP in terms of changes in cardiac output (stroke volume, SV), arterial stiffness (aortic pulse wave velocity, PWV), peripheral vascular resistances (PVR) and net and relative contributions of reflected waves to the aortic pulse amplitude. We included 154 subjects (mean age 11; range 4-16 years) assigned to one of two groups: normal peripheral BP (NBP, n = 101), defined as systolic and diastolic BP < 90th percentile, or high BP (HBP, n = 53), defined as average systolic and/or diastolic BP levels ≥90th percentile (curves for sex, age and body height). The HBP group included children with hypertensive and pre-hypertensive BP levels. After a first analysis, groups were compared excluding obese and dyslipidemic children. Peripheral and central aortic BP, PWV and pulse wave-derived parameters (augmentation index, forward and backward wave components' amplitude) were measured using gold-standard techniques, applanation tonometry (SphygmoCor) and oscillometry (Mobil-O-Graph). Independent of the presence of dyslipidemia and/or obesity, aortic systolic and pulse BP were higher in HBP than in NBP children. The increase in central BP could not be explained by an increase in the relative contribution of reflections to the aortic pressure wave, higher PVR or by an augmented peripheral reflection coefficient. Instead, the rise in central BP would be explained by an increase in the amplitude of both incident and reflected wave components.
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