Evidence map›Paper›PMID 27388479›Full record

ArticleBMC neuroscience2016

Abnormal white matter integrity in rapists as indicated by diffusion tensor imaging.

Chiao-Yun Chen, Adrian Raine, Kun-Hsien Chou, I-Yun Chen, Daisy Hung, Ching-Po Lin

Abstract read
In one paragraph

Article in BMC neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chiao-Yun ChenDepartment and Graduate Institute of Criminology, National Chung Cheng University, Chiayi, 621, Taiwan.
Adrian RaineDepartment of Criminology, Psychiatry, and Psychology, University of Pennsylvania, Philadelphia, PA, USA.
Kun-Hsien ChouBrain Research Center, National Yang-Ming University, Taipei, 112, Taiwan.
I-Yun ChenInstitute of Neuroscience, National Yang-Ming University, Taipei, 112, Taiwan.
Daisy HungInstitute of Cognitive Neuroscience, National Central University, Jhongli, Taiwan.
Ching-Po LinBrain Research Center, National Yang-Ming University, Taipei, 112, Taiwan. cplin@ym.edu.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent research has documented structural brain abnormalities in various criminal offenders. However, there have been few brain imaging studies of sex offenders, and none on white matter integrity. The current study tested the hypothesis that rapists, when compared to matched controls, would show abnormal cortical and subcortical white matter integrity.

resultsRapists showed significantly increased fractional anisotropy in the internal capsul e in the thalamus, caudate, and globus pallidus, and also in white matter tracts near the angular gyrus, posterior cingulate, frontal pole, lateral occipital cortex, and genu compared to controls matched for age, gender, and educational status. Reduced fractional anisotropy was observed in rapists in the posterior cingulum and in the inferior fronto-occipital fasciculus.

conclusionsTo our knowledge, this is the first study indicating white matter abnormalities in rapists. Findings indicate abnormalities in white matter connectivity in brain regions involved in reward/motivation and moral judgment, which may predispose rapists to be both over-responsive to sexual reward stimuli and also to make inappropriate moral decisions.

Indexed as

CriminalsDiffusion Tensor ImagingRapeAdultBrainHumansMagnetic Resonance ImagingMaleWhite MatterDiffusion tensor imagingMoral judgmentRapistRewardWhite matter

Identifiers

PMID27388479
PMCPMC4936222

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.