ArticleEuropean journal of nutrition2017
Effects of Lentinula edodes consumption on biochemical, hematologic and oxidative stress parameters in rats receiving high-fat diet.
Article in European journal of nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 18 citations in OpenAlex.
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- Nutritional and economic evaluation of fermented durian peel on laying duck performance and yolk omega profile.Journal of advanced veterinary and animal research · 2026Article
- Comparison of the Conventional, Chemical, and Ultrasound Extraction of Crude Polysaccharides and Their Properties fromFoods (Basel, Switzerland) · 2025Article
- Anti-Obesity Effect ofNutrients · 2023Article
- Edible Mushrooms as Novel Myco-Therapeutics: Effects on Lipid Level, Obesity and BMI.Journal of fungi (Basel, Switzerland) · 2022Review
- Ethnomycological Investigation in Serbia: Astonishing Realm of Mycomedicines and Mycofood.Journal of fungi (Basel, Switzerland) · 2021Article
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- Effect of mushrooms on obesity in animal models: study protocol for a systematic review and meta-analysis.Systematic reviews · 2019Article
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- Anti-Obesity Effects of Medicinal and Edible Mushrooms.Molecules (Basel, Switzerland) · 2018Review
- Hypolipidemic effect of Fragarianilgerrensis Schlecht. medicine compound on hyperlipidemic rats.Lipids in health and disease · 2018Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
purposeFunctional foods can prevent/reduce the risks related to obesity. Lentinula edodes is a highly nutritious mushroom rich in protein, vitamins and minerals. Some studies have demonstrated the hypocholesterolemic effects from L. edodes in high doses, which does not represent the consumption in humans. We evaluated ingestion of a realistic dose of L. edodes associated with a high-fat diet (HFD) on hematologic, biochemical and oxidative stress parameters.
methodsEighteen male Wistar rats were divided into three groups: control (normal diet); HFD; and HFD + L. edodes (100 mg/kg/day). After 30 days, blood was collected. Biochemical and hematologic parameters were analyzed, as well as oxidative stress biomarkers.
resultsThe HFD increased levels of total cholesterol and triglycerides. Lentinula edodes reduced these parameters significantly to concentrations found in the control group. The HFD increased levels of alanine transaminase and aspartate transaminase (markers of liver damage). Lentinula edodes returned the levels of these enzymes to normal levels and normalized serum levels of urea (which were also increased owing to consumption of the HFD). Lentinula edodes reduced levels of urea and glucose. Lipid peroxidation was increased in rats receiving the HFD, and L. edodes reduced malondialdehyde levels, thereby preventing oxidation of fatty acids.
conclusionsLentinula edodes was shown to have hypolipidemic, hypoglycemic, hepatoprotective and renoprotective features in doses that are suitable for humans.
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