Evidence map›Paper›PMID 27387890›Full record

ArticleJournal of physiology and biochemistry2016

Hypothermia can reverse hepatic oxidative stress damage induced by hypoxia in rats.

Manuel Vicente Garnacho-Castaño, Norma Alva, Sergio Sánchez-Nuño, Raquel G Bardallo, Jesús Palomeque, Teresa Carbonell

Abstract read
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In one paragraph

Article in Journal of physiology and biochemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Effects of Therapeutic Hypothermia on Normal and Ischemic Heart.Frontiers in cardiovascular medicine · 2021
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Manuel Vicente Garnacho-CastañoTecnoCampus Mataró-Maresme, College of Health Sciences, University of Pompeu Fabra, Ernest Lluch, 32 (Porta Laietana), 08302, Mataró-Barcelona, Spain. mgarnacho@tecnocampus.cat.
Norma AlvaDepartment of Cell Biology, Physiology and Inmunology, Faculty of Biology, University of Barcelona, 643 Diagonal Ave. (3rd floor), 08028, Barcelona, Spain.
Sergio Sánchez-NuñoDepartment of Cell Biology, Physiology and Inmunology, Faculty of Biology, University of Barcelona, 643 Diagonal Ave. (3rd floor), 08028, Barcelona, Spain.
Raquel G BardalloDepartment of Cell Biology, Physiology and Inmunology, Faculty of Biology, University of Barcelona, 643 Diagonal Ave. (3rd floor), 08028, Barcelona, Spain.
Jesús PalomequeDepartment of Cell Biology, Physiology and Inmunology, Faculty of Biology, University of Barcelona, 643 Diagonal Ave. (3rd floor), 08028, Barcelona, Spain.
Teresa CarbonellDepartment of Cell Biology, Physiology and Inmunology, Faculty of Biology, University of Barcelona, 643 Diagonal Ave. (3rd floor), 08028, Barcelona, Spain.
Universitat de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our previous findings demonstrated that hypothermia enhances the reduction potential in the liver and helps to maintain the plasmatic antioxidant pool. Here, we aimed to elucidate if hypothermia protects against hypoxia-induced oxidative stress damage in rat liver. Several hepatic markers of oxidative stress were compared in three groups of animals (n = 8 in each group): control normothermic group ventilated with room air and two groups under extreme hypoxia (breathing 10 % O

Indexed as

Hypothermia, InducedAldehydesAnimalsAntioxidantsChemical and Drug Induced Liver InjuryGlutathioneHypoxiaLipid PeroxidationLiverMaleNitric OxideNitric Oxide Synthase Type IIOxidation-ReductionOxidative StressOxygenProtein Carbonylation4-hydroxy-2-nonenalAldehydesAntioxidantsGlutathioneNitric OxideNitric Oxide Synthase Type IINos2 protein, ratOxygen4-HNE adductsHypoxiaLipid peroxidationNitric oxideProtein oxidationTherapeutic hypothermia

Identifiers

PMID27387890
OpenAlexW2463785499

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.