Evidence map›Paper›PMID 27387885›Full record

ArticleNature medicine2016

Follicular T helper cells: hotspots for HIV-1 persistence.

Mirko Paiardini, Mathias Lichterfeld

Abstract readComment
PubMed Publisher
In one paragraph

Article in Nature medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  6. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Mirko PaiardiniDepartment of Pathology, Emory University School of Medicine, Atlanta, Georgia, USA and at the Yerkes National Primate Research Center, Atlanta, Georgia, USA.
Mathias LichterfeldInfectious Disease Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA and at the Ragon Institute of Massachusetts General Hospital, MIT and Harvard University, Cambridge, Massachusetts, USA.

Funding

A Pilot Clinical Trial for HIV-1 EradicationU01AI117841 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI KURITZKES, DANIEL R., LICHTERFELD, MATHIAS · 2015 to 2020
$10.7M
Early Infant TreatmentU01AI114235 · NIAID · HARVARD SCHOOL OF PUBLIC HEALTH · PI KURITZKES, DANIEL R., LICHTERFELD, MATHIAS · 2014 to 2020
$5.1M
Central memory CD4 T cell infection: key role in ART response and HIV persistenceR01AI110334 · NIAID · EMORY UNIVERSITY · PI MARCONI, VINCENT CHARLES, PAIARDINI, MIRKO · 2013 to 2017
$4.4M
Quantification of the HIV-1 Reservoir by Immuno-PCRR01AI120008 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI HEREDIA, ALONSO, LICHTERFELD, MATHIAS · 2015 to 2019
$1.9M
Inhibitors of host kinases as molecular targets for immune defense against HIV-1R01AI098487 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI LICHTERFELD, MATHIAS · 2012 to 2015
$1.7M
Persistent Virus Reservoirs in SIV-infected MacaquesR33AI104278 · NIAID · EMORY UNIVERSITY · PI PAIARDINI, MIRKO · 2015 to 2017
$1.6M
Persistent Virus Reservoirs in SIV-infected MacaquesR21AI104278 · NIAID · EMORY UNIVERSITY · PI PAIARDINI, MIRKO, SILVESTRI, GUIDO · 2013 to 2014
$489k
Limiting HIV-1 persistence by targeting stem cell properties of CD4 T cellsR21AI106468 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI LICHTERFELD, MATHIAS · 2013 to 2014
$465k
NIAID NIH HHS R01 AI098487NIAID NIH HHS R01 AI110334NIAID NIH HHS R01 AI120008NIAID NIH HHS R21 AI104278NIAID NIH HHS R21 AI106468NIAID NIH HHS R33 AI104278NIAID NIH HHS U01 AI114235NIAID NIH HHS U01 AI117841
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HIV-1T-Lymphocytes, Helper-InducerHIV InfectionsHumans

Identifiers

PMID27387885

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.