Evidence map›Paper›PMID 27387876›Full record

ArticleEuropean radiology2017

High-resolution intracranial vessel wall MRI in an elderly asymptomatic population: comparison of 3T and 7T.

Anita A Harteveld, Anja G van der Kolk, H Bart van der Worp, Nikki Dieleman, Jeroen C W Siero, Hugo J Kuijf, Catharina J M Frijns, Peter R Luijten, Jaco J M Zwanenburg, Jeroen Hendrikse

Open access · hybridAbstract readComparative Study
In one paragraph

Article in European radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.

  1. MR Intracranial Vessel Wall Imaging: A Systematic Review.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2020
    Pooled it
  2. Trial
  3. Article
  4. Review
  5. Observational
  6. Inter-rater reliability of atherosclerotic plaque enhancement on 7 T vessel wall MRI: Comparison with quantitative analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  7. Article
  8. Review
  9. High resolution 7T MR imaging in characterizing culprit intracranial atherosclerotic plaques.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  10. A radiomic model based on 7T intracranial vessel wall imaging for identification of culprit middle cerebral artery plaque associated with subcortical infarctions.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Article
  11. Article
  12. Article
  13. Review
  14. Time-of-flight MRA of intracranial vessels at 7 T.European radiology experimental · 2024
    Article
  15. Review
  16. Article
  17. Vessel Wall Imaging of Intracranial Arteries: Fundamentals and Clinical Applications.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2023
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Anita A HarteveldDepartment of Radiology, University Medical Center Utrecht, Postbox 85500, 3508 GA, Utrecht, The Netherlands. a.a.harteveld-2@umcutrecht.nl.
Anja G van der KolkDepartment of Radiology, University Medical Center Utrecht, Postbox 85500, 3508 GA, Utrecht, The Netherlands.
H Bart van der WorpDepartment of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.
Nikki DielemanDepartment of Radiology, University Medical Center Utrecht, Postbox 85500, 3508 GA, Utrecht, The Netherlands.
Jeroen C W SieroDepartment of Radiology, University Medical Center Utrecht, Postbox 85500, 3508 GA, Utrecht, The Netherlands.
Hugo J KuijfImage Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands.
Catharina J M FrijnsDepartment of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.
Peter R LuijtenDepartment of Radiology, University Medical Center Utrecht, Postbox 85500, 3508 GA, Utrecht, The Netherlands.
Jaco J M ZwanenburgDepartment of Radiology, University Medical Center Utrecht, Postbox 85500, 3508 GA, Utrecht, The Netherlands.
Jeroen HendrikseDepartment of Radiology, University Medical Center Utrecht, Postbox 85500, 3508 GA, Utrecht, The Netherlands.
University Medical Center Utrecht · NL

Funding

European Research Council 337333European Research Council 637024
6 · The paper itself

Abstract

objectivesSeveral intracranial vessel wall sequences have been described in recent literature, with either 3-T or 7-T magnetic resonance imaging (MRI). In the current study, we compared 3-T and 7-T MRI in visualising both the intracranial arterial vessel wall and vessel wall lesions.

methodsTwenty-one elderly asymptomatic volunteers were scanned by 3-T and 7-T MRI with an intracranial vessel wall sequence, both before and after contrast administration. Two raters scored image quality, and presence and characteristics of vessel wall lesions.

resultsVessel wall visibility was equal or significantly better at 7 T for the studied arterial segments, even though there were more artefacts hampering assessment. The better visualisation of the vessel wall at 7 T was most prominent in the proximal anterior cerebral circulation and the posterior cerebral artery. In the studied elderly asymptomatic population, 48 vessel-wall lesions were identified at 3 T, of which 7 showed enhancement. At 7 T, 79 lesions were identified, of which 29 showed enhancement. Seventy-one percent of all 3-T lesions and 59 % of all 7-T lesions were also seen at the other field strength.

conclusionsDespite the large variability in detected lesions at both field strengths, we believe 7-T MRI has the highest potential to identify the total burden of intracranial vessel wall lesions. KEY POINTS: • Intracranial vessel wall visibility was equal or significantly better at 7-T MRI • Most vessel wall lesions in the cerebral arteries were found at 7-T MRI • Many intracranial vessel wall lesions showed enhancement after contrast administration • Large variability in detected intracranial vessel wall lesions at both field strengths • Seven-tesla MRI has the highest potential to identify total burden of intracranial atherosclerosis.

Indexed as

AgedArtifactsCerebral ArteriesCerebrovascular CirculationContrast MediaFemaleGeriatric AssessmentHumansImage EnhancementIntracranial ArteriosclerosisMagnetic Resonance ImagingMaleProspective StudiesContrast MediaCerebral arteriesCerebrovascular disordersIntracranial atherosclerosisMagnetic resonance imagingNeuroimaging

Identifiers

PMID27387876
PMCPMC5334422
OpenAlexW2473445601

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.