Evidence map›Paper›PMID 27387665›Full record

ArticlePloS one2016

Characterization of Vaginal Escherichia coli Isolated from Pregnant Women in Two Different African Sites.

Emma Sáez-López, Anélsio Cossa, Rachid Benmessaoud, Lola Madrid, Cinta Moraleda, Sonia Villanueva, Houssain Tligui, Benilde Moiane, Hassan Alami, Sérgio Massora and 6 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 30 citations in OpenAlex.

  1. Research Progress on perinatalFrontiers in microbiology · 2026
    Review
  2. Population characteristics of pathogenicFrontiers in microbiology · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 3 countries.

Emma Sáez-LópezDepartment of Clinical Microbiology, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Anélsio CossaCentro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.
Rachid BenmessaoudISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Lola MadridISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Cinta MoraledaISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Sonia VillanuevaDepartment of Clinical Microbiology, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Houssain TliguiÉquipe de Recherche en Santé et Nutrition du Couplé Mère Enfant, Faculté de Médecine et de Pharmacie, Université Mohammed V Souissi, Rabat, Morocco.
Benilde MoianeCentro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.
Hassan AlamiÉquipe de Recherche de Périnatologie, Université Mohammed V Souissi, Rabat, Morocco.
Sérgio MassoraCentro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.
Rachid BezadÉquipe de Recherche de Périnatologie, Université Mohammed V Souissi, Rabat, Morocco.
Inacio MandomandoCentro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.
Jordi BoschDepartment of Clinical Microbiology, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Jordi VilaDepartment of Clinical Microbiology, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Quique BassatISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Sara M SotoDepartment of Clinical Microbiology, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Barcelona Institute for Global Health · ESManhiça Health Research Centre · MZUniversitat de Barcelona · ESMohammed V University · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The relevance of vaginal colonization of pregnant women by Escherichia coli is poorly understood, despite these strains sharing a similar virulence profile with other extraintestinal pathogenic E. coli producing severe obstetric and neonatal infections. We characterized the epidemiology, antimicrobial susceptibility and virulence profiles of 84 vaginal E. coli isolates from pregnant women from Rabat (Morocco) and Manhiça (Mozambique), two very distinct epidemiological settings. Low levels of antimicrobial resistance were observed to all drugs tested, except for trimethoprim-sulfamethoxazole in Manhiça, where this drug is extensively used as prophylaxis for opportunistic HIV infections. The most prevalent virulence factors were related to iron acquisition systems. Phylogroup A was the most common in Rabat, while phylogroups E and non-typeable were the most frequent in Manhiça. Regardless of the apparently "low virulence" of these isolates, the frequency of infections is higher and the outcomes more devastating in constrained-resources conditions, especially among pregnant women and newborns.

Indexed as

Anti-Bacterial Agentsbeta-LactamasesDrug Resistance, BacterialEscherichia coliEscherichia coli InfectionsFemaleHIV InfectionsHumansMicrobial Sensitivity TestsMoroccoMozambiquePhylogenyPregnancyPregnancy Complications, InfectiousPrevalenceTrimethoprim, Sulfamethoxazole Drug CombinationAnti-Bacterial Agentsbeta-LactamasesTrimethoprim, Sulfamethoxazole Drug CombinationVirulence Factors

Identifiers

PMID27387665
PMCPMC4936694
OpenAlexW2464883495

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.