SynthesisScientific reports2016
Effect of caesarean section on maternal and foetal outcomes in acute fatty liver of pregnancy: a systematic review and meta-analysis.
Synthesis in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Safety and efficacy of plasmapheresis in treatment of acute fatty liver of pregnancy-a systematic review and meta-analysis.Frontiers in medicine · 2024Pooled it
- Treating acute fatty liver of pregnancy with artificial liver support therapy: Systematic review.Medicine · 2018Pooled it
- Acute Fatty Liver of Pregnancy Presenting With Isolated Nausea and Vomiting in the Third Trimester: A Case Report.Cureus · 2026Article
- Acute fatty liver of pregnancy in the context of normal-dose acetaminophen exposure: a case report.BMC pregnancy and childbirth · 2026Article
- Article
- Acute kidney injury associated with acute fatty liver of pregnancy: An update on a rare clinical entity.World journal of nephrology · 2025Review
- Risk factors in patients with acute fatty liver of pregnancy: the role of abortion, total bilirubin and serum creatinine.Archives of gynecology and obstetrics · 2024Article
- Risk factors and outcomes associated with pregnancy-related acute kidney injury in a high-risk cohort of women in Nigeria.Journal of nephrology · 2024Article
- A 24-Year-Old Woman Presenting in the Third Trimester of Pregnancy with Nausea, Vomiting, and Abdominal Pain and Diagnosed with Acute Fatty Liver of Pregnancy.The American journal of case reports · 2022Article
- Does the appearance of the cutaneous scar after cesarean section reflect the residual myometrial thickness?Archives of gynecology and obstetrics · 2021Article
- Sickle cell anaemia in vaso-occlusive crisis and acute fatty liver of pregnancy: a case report.Ghana medical journal · 2020Article
- Acute fatty liver of pregnancy cases in a maternal and child health hospital of China: Three case reports.Medicine · 2020Article
- Pregnancy outcomes of patients with acute fatty liver of pregnancy: a case control study.BMC pregnancy and childbirth · 2020Article
- HELLP Syndrome or Acute Fatty Liver of Pregnancy: A Differential Diagnostic Challenge: Common Features and Differences.Geburtshilfe und Frauenheilkunde · 2020Article
- Pregnancy-associated liver disease: a curriculum-based review.Frontline gastroenterology · 2018Review
- [Clinical features and treatment of acute fatty liver of pregnancy complicated by acute liver failure].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2017Article
- Indian National Association for the Study of the Liver-Federation of Obstetric and Gynaecological Societies of India Position Statement on Management of Liver Diseases in Pregnancy.Journal of clinical and experimental hepatologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several studies have reported a positive association between caesarean section for expeditious pregnancy termination and perinatal outcomes in acute fatty liver of pregnancy (AFLP); however, the risks remain unclear and independent studies have reported conflicting findings. In this meta-analysis, we aimed to confirm the relationship between caesarean section and perinatal outcomes in AFLP. The PubMed, Embase, and China National Knowledge Infrastructure databases were searched (until July 17, 2015) for observational clinical studies focusing on the association between caesarean section and perinatal outcomes in AFLP. Data were extracted and processed independently by 2 authors. We also compared caesarean section with vaginal delivery to further investigate this relationship. We observed that 2 of the 3 primary outcomes in caesarean section exhibited positive effects-the maternal mortality rate was 44% lower (relative risk [RR], 0.56 [0.41-0.76]) and perinatal mortality rate was also reduced (RR, 0.52 [0.38-0.71]), compared to those for vaginal delivery. We did not find any associations between caesarean section and perinatal outcomes in AFLP in terms of neonatal mortality type and maternal multiple organ complications. These findings emphasise the significant prognostic value and clinical implications of caesarean section in AFLP, and suggest that the adverse outcomes should be reduced.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.