Evidence map›Paper›PMID 27387307›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2017

Progression of medial compartmental osteoarthritis 2-8 years after lateral closing-wedge high tibial osteotomy.

M R Huizinga, J Gorter, A Demmer, S M A Bierma-Zeinstra, R W Brouwer

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05840887 (Knee Osteotomy Associated With Allograft Meniscus Transplantation in Patients With Altered Mechanical Axis, Meniscectomy Outcomes, and Osteoarthritis), which is not on this map. Cited by 16 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 4 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05840887 narecruitingnot on this mapstarted 2023, after this paper: background citation

Knee Osteotomy Associated With Allograft Meniscus Transplantation in Patients With Altered Mechanical Axis, Meniscectomy Outcomes, and Osteoarthritis: Clinical, Biomechanical, and Biological Evaluation

TypeinterventionalSponsorIstituto Ortopedico RizzoliRan2023 to 2026Enrolled52ConditionsMalalignment, Bone, Osteoarthritis, KneeArmsKnee osteotomy associated with meniscal allograft transplantation, Knee osteotomy
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 33 citations in OpenAlex.

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  4. Indications and outcomes of simultaneous high tibial osteotomy and ACL reconstruction.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

M R HuizingaDepartment of Orthopaedic Surgery, Martini Hospital, PO Box 30033, 9700 RM, Groningen, The Netherlands. m.r.huizinga@mzh.nl.
J GorterDepartment of Orthopaedic Surgery, Martini Hospital, PO Box 30033, 9700 RM, Groningen, The Netherlands.
A DemmerDepartment of Orthopaedic Surgery, Martini Hospital, PO Box 30033, 9700 RM, Groningen, The Netherlands.
S M A Bierma-ZeinstraDepartment of Orthopaedics and General Practice, University Medical Center Rotterdam, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
R W BrouwerDepartment of Orthopaedic Surgery, Martini Hospital, PO Box 30033, 9700 RM, Groningen, The Netherlands.
Martini Ziekenhuis · NLErasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe primary purpose of this study is to investigate the progression of medial osteoarthritis (OA) following lateral closing-wedge high tibial osteotomy (HTO). Secondary outcomes included functional and pain scores.

methodsThis prospective cohort study analysed 298 patients treated with lateral closing-wedge HTO surgery for medial compartmental OA. OA progression was measured by comparing the minimum joint space width (mJSW) and Kellgren-Lawrence (KL) score on radiographs preoperatively and postoperatively. The WOMAC score and NRS score for pain were obtained preoperatively and postoperatively to assess secondary outcomes. Failure was defined as revision surgery; survival was estimated.

resultsMean follow-up was 5.2 ± 1.8 years (range 2-8.5). Mean preoperative mJSW was 3.4 ± 1.6 mm, which changed nonsignificantly (p = 0.51) to 3.4 ± 1.7 mm postoperatively. Mean annual joint space narrowing was 0.02 ± 0.34 mm/year. Progression to 1 KL grade or more was seen in 132 (44 %) patients, and annual risk of KL progression was 8.6 %. No KL progression was seen in 56 % of patients. Mean NRS decreased from 7.3 ± 1.5 to 3.5 ± 2.5 (p < 0.001). WOMAC scores decreased from 48.0 ± 17.2 to 23.6 ± 19.7 (p < 0.001). Failure was seen in 21 patients.

conclusionCompared to demographic data in the literature, valgus high tibial osteotomy seems to reduce the progression of OA, reduces pain and improves knee function in patients with medial compartment OA and a varus alignment. LEVEL OF EVIDENCE: III.

Indexed as

Disease ProgressionOutcome Assessment, Health CareAdultAgedFemaleHumansKnee JointMaleMiddle AgedOsteoarthritis, KneeOsteotomyPostoperative PeriodProspective StudiesRadiologyTibiaTime FactorsFailureHigh tibial osteotomyJoint spaceOsteoarthritisProgression

Identifiers

PMID27387307
OpenAlexW2461919422

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.