ArticleBMC cancer2016
Pre-diagnostic body mass index and weight change in relation to colorectal cancer survival among incident cases from a population-based cohort study.
Article in BMC cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Body mass index, weight change, and cancer prognosis: a meta-analysis and systematic review of 73 cohort studies.ESMO open · 2024Pooled it
- Association between prediagnostic risk factors and survival after colorectal cancer diagnosis in Golesten cohort study.Scientific reports · 2025Article
- Feasibility of a 12-Month Exercise Intervention in Postsurgical Colorectal Cancer Patients.Translational sports medicine · 2023Article
- Article
- Prediction of cancer survivors' mortality risk in Korea: a 25-year nationwide prospective cohort study.Epidemiology and health · 2022Article
- Article
- Heparan Sulfate Proteoglycans in Human Colorectal Cancer.Analytical cellular pathology (Amsterdam) · 2018Review
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhether excess body weight influences colorectal cancer (CRC) survival is unclear. We studied pre-diagnostic body mass index (BMI) and weight change in relation to CRC-specific mortality among incident CRC cases within a large, Norwegian cohort.
methodsParticipants' weight was measured at health examinations up to three times between 1974 and 1988. CRC cases were identified through linkage with the Norwegian Cancer Registry. In total, 1336 men and 1180 women with a weight measurement >3 years prior to diagnosis were included in analyses. Hazard ratios (HRs) and confidence intervals (CIs) were estimated with Cox regression.
resultsDuring a mean follow-up of 5.8 years, 507 men and 432 women died from CRC. Obesity (BMI ≥30 kg/m(2)) was associated with higher CRC-specific mortality than normal weight (BMI 18.5-25 kg/m(2)) in men with proximal colon cancer, HR = 1.85 (95 % CI 1.08-3.16) and in women with rectal cancer, HR = 1.93 (95 % CI 1.13-3.30). Weight gain was associated with higher CRC-specific mortality in women with CRC, colon cancer, and distal colon cancer, HRs per 5 kg weight gain were 1.18 (95 % CI 1.01-1.37), 1.22 (95 % CI 1.02-1.45), and 1.40 (95 % CI 1.01-1.95), respectively. Weight gain was not significantly associated with survival in men.
conclusionsMaintaining a healthy weight may benefit CRC survival, at least in women.
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