Evidence map›Paper›PMID 27386937›Full record

ReviewArteriosclerosis, thrombosis, and vascular biology2016

2014 Jeffrey M. Hoeg Award Lecture: Transcriptional Control of Monocyte Development.

Yanfang Peipei Zhu, Graham D Thomas, Catherine C Hedrick

Open access · bronzeAbstract readReview
In one paragraph

Review in Arteriosclerosis, thrombosis, and vascular biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 70 citations in OpenAlex.

  1. Monocyte-derived macrophages and their roles in ischemic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Review
  2. Review
  3. Article
  4. Impaired CAMK4 Activity Limits Atherosclerosis and Reprograms Myelopoiesis.Arteriosclerosis, thrombosis, and vascular biology · 2025
    Article
  5. Review
  6. Neutrophils: a new target for postoperative cognitive dysfunction.Apoptosis : an international journal on programmed cell death · 2025
    Review
  7. Review
  8. Article
  9. scBlood: A comprehensive single-cell accessible chromatin database of blood cells.Computational and structural biotechnology journal · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Circulating monocytes in acute pancreatitis.Frontiers in immunology · 2022
    Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yanfang Peipei ZhuFrom the Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, CA.
Graham D ThomasFrom the Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, CA.
Catherine C HedrickFrom the Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, CA. Hedrick@lji.org.
La Jolla Institute for Immunology · US

Funding

ROLE OF LIPOXYGENASES IN ATHEROGENESIS IN DIABETES MELLITUSP01HL055798 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI HEDRICK, CATHERINE C · 1995 to 2016
$28.4M
Project 4: APOB-specific CD4 and CD8 T cells exacerbate atherosclerosisP01HL136275 · NHLBI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI Catherine C Hedrick · 2017 to 2026
$25.5M
Transcriptional Control of Monocyte DevelopmentR01HL134236 · NHLBI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI HEDRICK, CATHERINE C · 2016 to 2019
$2.5M
Functions of Nonclassical Monocytes in the VasculatureR01CA202987 · NCI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI HEDRICK, CATHERINE C · 2016 to 2020
$2.2M
Nuclear Receptors in Myeloid Development, Inflammation, and AtherosclerosisR01HL118765 · NHLBI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI HEDRICK, CATHERINE C · 2013 to 2016
$2.2M
NCI NIH HHS R01 CA202987NHLBI NIH HHS P01 HL055798NHLBI NIH HHS P01 HL136275NHLBI NIH HHS R01 HL118765NHLBI NIH HHS R01 HL134236
6 · The paper itself

Abstract

Monocytes and macrophages are key immune cells involved in the early progression of atherosclerosis. Transcription factors that control their development in the bone marrow are important therapeutic targets to control the numbers and functions of these cells in disease. This review highlights what is currently known about the transcription factors that are critical for monocyte development.

Indexed as

Cell DifferentiationTranscription, GeneticAnimalsBone Marrow CellsCellular MicroenvironmentGene Expression RegulationGenotypeHematopoiesis, ExtramedullaryHumansMicroRNAsMonocytesMyelopoiesisPhenotypeTranscription FactorsMicroRNAsTranscription Factorsatherosclerosisbone marrowmicroRNAsmonocytestranscription factors

Identifiers

PMID27386937
PMCPMC5828163
OpenAlexW2512528003

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.