ArticleScience advances2016
Arrays of microscopic organic LEDs for high-resolution optogenetics.
Article in Science advances, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 78 citations in OpenAlex.
- Origin of Enhanced Efficiency and Reduced Roll-Off in Organic Light-Emitting Diodes Based on Pt(II) Complexes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Chronically implantable μLED arrays for optogenetic cortical surface stimulation in mice.Nature communications · 2026Article
- Design considerations for optogenetic applications of soft micro-LED-based device systems across diverse nervous systems.Bioactive materials · 2025Review
- Wireless magnetoelectrically powered organic light-emitting diodes.Science advances · 2024Article
- Biohybrid Photonic Platform for Subcellular Stimulation and Readout of In Vitro Neurons.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Review
- Emerging trends in the development of flexible optrode arrays for electrophysiology.APL bioengineering · 2023Review
- Review
- Behavioral optogenetics in nonhuman primates; a psychological perspective.Current research in neurobiology · 2023Review
- An improved platform for cultured neuronal network electrophysiology: multichannel optogenetics integrated with MEAs.European biophysics journal : EBJ · 2022Article
- Progress, Opportunities, and Challenges of Magneto-Plasmonic Nanoparticles under Remote Magnetic and Light Stimulation for Brain-Tissue and Cellular Regeneration.Nanomaterials (Basel, Switzerland) · 2022Review
- Article
- Platforms for Optogenetic Stimulation and Feedback Control.Frontiers in bioengineering and biotechnology · 2022Review
- Identification of the Key Parameters for Horizontal Transition Dipole Orientation in Fluorescent and TADF Organic Light-Emitting Diodes.Advanced materials (Deerfield Beach, Fla.) · 2021Review
- Segment-specific optogenetic stimulation in Drosophila melanogaster with linear arrays of organic light-emitting diodes.Nature communications · 2020Article
- Recent advances in bioelectronics chemistry.Chemical Society reviews · 2020Review
- Controlling the behaviour of Drosophila melanogaster via smartphone optogenetics.Scientific reports · 2020Article
- Ultraflexible organic light-emitting diodes for optogenetic nerve stimulation.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Single-Cell Optogenetic Control of Calcium Signaling with a High-Density Micro-LED Array.iScience · 2019Article
- Thermal constraints on in vivo optogenetic manipulations.Nature neuroscience · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Optogenetics is a paradigm-changing new method to study and manipulate the behavior of cells with light. Following major advances of the used genetic constructs over the last decade, the light sources required for optogenetic control are now receiving increased attention. We report a novel optogenetic illumination platform based on high-density arrays of microscopic organic light-emitting diodes (OLEDs). Because of the small dimensions of each array element (6 × 9 μm(2)) and the use of ultrathin device encapsulation, these arrays enable illumination of cells with unprecedented spatiotemporal resolution. We show that adherent eukaryotic cells readily proliferate on these arrays, and we demonstrate specific light-induced control of the ionic current across the membrane of individual live cells expressing different optogenetic constructs. Our work paves the way for the use of OLEDs for cell-specific optogenetic control in cultured neuronal networks and for acute brain slices, or as implants in vivo.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.