ArticleEndoscopic ultrasound
Characteristic endoscopic ultrasound findings of ampullary lesions that predict the need for surgical excision or endoscopic ampullectomy.
Article in Endoscopic ultrasound. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- A continuous visualization workflow for endoscopic papillectomy using balloon-assisted endoscopic ultrasound and direct cholangioscopy.Endoscopy · 2026Article
- Safety and efficacy of endoscopic papillectomy for duodenal papillary adenomas: A single-center retrospective study.World journal of gastrointestinal surgery · 2026Article
- Endoscopic Ultrasonography is a Promising Tool for Preoperative Prediction of the Operability of Pancreatic Carcinoma.Journal of gastrointestinal cancer · 2022Article
- Surgical ampullectomy: A comprehensive review.World journal of gastrointestinal surgery · 2021Review
- Transduodenal ampullectomy for ampullary tumors.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2017Article
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Authors and funding
7 authors.
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Abstract
BACKGROUND AND
objectivesThe management of ampullary lesions has evolved to include endoscopic ampullectomy (EA) as a curative approach to cancers of the ampulla of Vater. With this change comes a need to risk-stratify patients at initial diagnosis. MATERIALS AND
methodsPatients with verified ampullary lesions (N = 50) were analyzed in a case-control design. We evaluated endoscopic ultrasound (EUS) data to define characteristics that yield a high sensitivity in selecting candidates for EA.
resultsUsing data from previously published studies yielded a sensitivity of 0.765 in appropriately identifying the 34 surgical cases. Expanding these characteristics increased the sensitivity of EUS to 0.971 in identifying surgical candidates. Additionally, of advanced disease cases, the expanded characteristics correctly identified these cases with a sensitivity of 1.0-improved over 0.708 using prior published data.
conclusionEA should be strongly considered if ampullary lesions are found to fit the following characteristics after EUS evaluation: lesion size <2.5 cm, invasion ≤4 mm, pancreatic duct dilatation ≤3 mm, ≤T1 lesion, no lymph nodes present, and no ductal stent in place. Furthermore, EUS data can be used to identify all high-risk lesions. With these characteristics identified, clinicians are better able to risk-stratify patients using EUS as either appropriate for or too high-risk for endoscopic resection.
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