ArticleSpringerPlus2016
The relationship between quantitative measures of disc height and disc signal intensity with Pfirrmann score of disc degeneration.
Article in SpringerPlus, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Quantification of intervertebral disc degeneration using dual-energy computed tomography collagen maps: a comparative study with MRI Pfirrmann grading.Scientific reports · 2026Article
- MRI-based deep learning radiomics model for automated classification of disc degeneration in the lumbar spine.Scientific reports · 2026Article
- Parametric Finite Element Evaluation of Load Redistribution Under Progressive Lumbar Disc Degeneration.Bioengineering (Basel, Switzerland) · 2026Article
- Progression of lumbar disc degeneration: A 14-year follow-up study examining Pfirrmann grading and its individual disc components.Acta radiologica open · 2025Article
- Review
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- Sociodemographic Influences on Lumbar Disc Degeneration Severity and the Diagnostic Potential of Disc‑CSF Signal Ratio: Insights from a South East Asia Population Study.Journal of the Belgian Society of Radiology · 2025Article
- Relation of lumbar intervertebral disc height and severity of disc degeneration based on Pfirrmann scores.Heliyon · 2023Article
- Article
- Association between periodontitis and disc structural failure in older adults with lumbar degenerative disorders: A prospective cohort study.BMC surgery · 2023Article
- Effect of Percutaneous Kyphoplasty on the progression of intervertebral disc degeneration: a retrospective cohort study.Journal of orthopaedic surgery and research · 2023Article
- Effect of bone cement distribution on adjacent disc degeneration after vertebral augmentation for osteoporotic vertebral compression fractures in aging patients.Frontiers in surgery · 2023Article
- MRI Assessment of the Early Disc Degeneration Two Levels above Fused Lumbar Spine Segment: A Comparison after Unilateral and Bilateral Transforaminal Lumbar Interbody Fusion (TLIF) Procedure.Journal of clinical medicine · 2022Article
- Novel Methods to Measure Height and Volume in Healthy and Degenerated Lumbar Discs in MRIs: A Reliability Assessment Study.Diagnostics (Basel, Switzerland) · 2022Article
- New MR-based measures for the evaluation of age-related lumbar paraspinal muscle degeneration.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021Article
- Expression of ANGPTL4 in Nucleus Pulposus Tissues Is Associated with Intervertebral Disc Degeneration.Disease markers · 2021Article
- Quantitative assessment of the lumbar intervertebral disc via T2 shows excellent long-term reliability.PloS one · 2021Article
- Correlation Between Expression of High Temperature Requirement Serine Protease A1 (HtrA1) in Nucleus Pulposus and T2 Value of Magnetic Resonance Imaging.Medical science monitor : international medical journal of experimental and clinical research · 2017Article
- Asymmetrical and smaller size of trunk muscles in combat sports athletes with lumbar intervertebral disc degeneration.SpringerPlus · 2016Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo assess the relationship between quantitative measures of disc height and signal intensity with the Pfirrmann disc degeneration scoring system and to test the inter-rater reliability of the quantitative measures.
methodsParticipants were 76 people who had recently recovered from their last episode of acute low back pain and underwent MRI scan on a single 3T machine. At all 380 lumbar discs, quantitative measures of disc height and signal intensity were made by 2 independent raters and compared to Pfirrmann scores from a single radiologist. For quantitative measures of disc height and signal intensity a "raw" score and 2 adjusted ratios were calculated and the relationship with Pfirrmann scores was assessed. The inter-tester reliability of quantitative measures was also investigated.
resultsThere was a strong linear relationship between quantitative disc signal intensity and Pfirrmann scores for grades 1-4, but not for grades 4 and 5. For disc height only, Pfirrmann grade 5 had significantly reduced disc height compared to all other grades. Results were similar regardless of whether raw or adjusted scores were used. Inter-rater reliability for the quantitative measures was excellent (ICC > 0.97).
conclusionsQuantitative measures of disc signal intensity were strongly related to Pfirrmann scores from grade 1 to 4; however disc height only differentiated between grade 4 and 5 Pfirrmann scores. Using adjusted ratios for quantitative measures of disc height or signal intensity did not significantly alter the relationship with Pfirrmann scores.
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