Evidence map›Paper›PMID 27386060›Full record

ArticleCaspian journal of internal medicine2016

Influence of supplemental vitamin D on intensity of benign paroxysmal positional vertigo: A longitudinal clinical study.

Mahboobeh Sheikhzadeh, Yones Lotfi, Abdollah Mousavi, Behzad Heidari, Mohsen Monadi, Enayatollah Bakhshi

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Caspian journal of internal medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05863949 (STOP Vertigo), which is not on this map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05863949 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

STOP Vertigo: Supplementation of Vitamin D for Termination of Recurrences From Benign Paroxysmal Positional Vertigo

TypeinterventionalSponsorOttawa Hospital Research InstituteRan2025 to 2026Enrolled860ConditionsBPPV, Benign Paroxysmal Positional Vertigo, Vertigo, Vertigo, PeripheralArmsvitamin D +/- calcium, Placebo
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Association between bone mineral density and benign paroxysmal positional vertigo: a meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2019
    Pooled it
  3. Association of benign paroxysmal positional vertigo with vitamin D deficiency: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018
    Pooled it
  4. Article
  5. Evaluation of a questionnaire as a screening tool for benign paroxysmal position vertigo.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
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  11. Review
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  15. A Relationship Between Blood Levels of Otolin-1 and Vitamin D.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2018
    Article
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  17. Age-Related Increase in Blood Levels of Otolin-1 in Humans.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2017
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mahboobeh SheikhzadehDepartment of Audiology, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Yones LotfiUniversity of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Abdollah MousaviTehran University of Medical Sciences, Tehran, Iran.
Behzad HeidariMobility Impairment Research Center, Babol University of Medical Sciences, Babol, Iran.
Mohsen MonadiDepartment of Audiology, Babol University of Medical Sciences, Babol, Iran.
Enayatollah BakhshiDepartment of Statistics, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
University of Social Welfare and Rehabilitation Sciences · IRBabol University of Medical Sciences · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBenign paroxysmal positional vertigo (BPPV) is linked to vitamin D deficiency. This clinical trial aimed to determine the influence of vitamin D supplementation on intensity of BPPV.

methodsThe study population was selected consecutively and the diagnosis of BPPV was made by history and clinical examination and exclusion of other conditions. Intensity of BPVV was assessed based on VAS score (0-10). Serum 25-hydroxyvitamin D (25-OHD) was measured using ELISA method and levels < 20 ng/ml was considered a deficiency. All patients received rehabilitation treatment using Epley's maneuver one time per week for one month. Serum 25-OHD deficient patients were classified as treated and non-treated groups (rehabilitation with or without 50.000 IU cholecalciferol weekly for two months).The results of treatment were compared with vitamin D sufficient group as control. All patients were followed-up for 6 months.

resultsAfter two months of treatment, in both vitamin D treated and non-treated groups the intensity of BPPV decreased significantly as compared with control (P=0.001 for both groups) but at endpoint, the intensity of BPPV aggravated and regressed to the baseline value in vitamin D deficient non-treated group (P=0.001) whereas, in vitamin D treated group, improvement of BPPV remained stable and unchanged over the study period.

conclusionThis study indicates that correction of vitamin D deficiency in BPPV provides additional benefit to rehabilitation therapy (Epley maneuver) regarding duration of improvement. These findings suggest serum 25-OHD measurement in recurrent BPPV.

Indexed as

Benign paroxysmal positional vertigoIntensityRehabilitation Therapy.Vitamin D

Identifiers

PMID27386060
PMCPMC4913711
OpenAlexW2419560750

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.