ArticleThoracic cancer2016
Clinical outcomes of video-assisted thoracic surgery and stereotactic body radiation therapy for early-stage non-small cell lung cancer: A meta-analysis.
Article in Thoracic cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 25 citations in OpenAlex.
- Article
- Radiation-Induced Lung Injury CT Features: Early Non-Small Cell Lung Cancer SBRT Prognosticators.Current medical imaging · 2025Article
- Relapse predictability of topological signature on pretreatment planning CT images of stage I non-small cell lung cancer patients before treatment with stereotactic ablative radiotherapy.Thoracic cancer · 2022Article
- A combined predictive model based on radiomics features and clinical factors for disease progression in early-stage non-small cell lung cancer treated with stereotactic ablative radiotherapy.Frontiers in oncology · 2022Article
- Advances and controversies in the management of early stage non-small cell lung cancer.World journal of clinical oncology · 2021Review
- Lung stereotactic body radiation therapy for elderly patients aged ≥ 80 years with pathologically proven early-stage non-small cell lung cancer: a retrospective cohort study.Radiation oncology (London, England) · 2021Article
- Long Term Results of Single-Fraction Carbon-Ion Radiotherapy for Non-small Cell Lung Cancer.Cancers · 2020Article
- Stereotactic body radiation therapy for early-stage non-small-cell lung cancer in octogenarians and older: an alternative treatment.Journal of radiation research · 2020Article
- Surgery and stereotactic body radiotherapy for early-stage non-small cell lung cancer: prospective clinical trials of the past, the present, and the future.General thoracic and cardiovascular surgery · 2020Review
- Influence of tumor characteristics on correction differences between cone-beam computed tomography-guided patient setup strategies in stereotactic body radiation therapy for lung cancer.Thoracic cancer · 2020Article
- Surgery and stereotactic body radiotherapy for early stage non-small cell lung cancer: review of meta-analyses.Journal of thoracic disease · 2019Review
- The surgeon thunderbolts in 2016 lung cancer literature.Annals of translational medicine · 2018Article
- Clinical results of proton beam therapy for elderly patients with non-small cell lung cancer.Radiation oncology (London, England) · 2018Article
- Sarcopenia is a predictor of outcomes after lobectomy.Journal of thoracic disease · 2018Article
- Implications for high-precision dose radiation therapy planning or limited surgical resection after percutaneous computed tomography-guided lung nodule biopsy using a tract sealant.Advances in radiation oncologyArticle
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe compared video-assisted thoracoscopic surgery (VATS) lobectomy and stereotactic body radiation therapy (SABR) to explore clinical outcomes in the treatment of patients with early stage NSCLC.
methodsMajor medical databases were systematically searched to identify studies on VATS and SBRT published between January 2010 and October 2015. English publications of stage I and II NSCLC with adequate patients and SBRT doses were included. A multivariate random effects model was used to perform meta-analysis to compare overall survival (OS) and disease-free survival (DFS) between VATS and SBRT, adjusting for median age and operable patient numbers.
resultsThirteen VATS (3436 patients) and 24 SBRT (4433) studies were eligible. The median age and follow-up duration was 68 years and 42 months for VATS and 74 years and 29.4 months for SBRT patients. After adjusting for the proportion of operable patients and median age, the estimated OS rates at one, two, three, and five years with VATS were 94%, 89%, 84%, and 69% compared with 96%, 94%, 89%, and 82% for SBRT. The estimated DFS rates at one, two, three, and five years with VATS were 97%, 93%, 87%, and 77% compared with 86%, 80%, 73%, and 58% for SBRT.
conclusionBefore adjustment, patients treated with SBRT had poorer clinical outcomes compared to those treated with VATS. A substantial difference between median age and operability exists between patients treated with SBRT and VATS. After adjusting for these differences, OS and DFS did not differ significantly between the two techniques.
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